Clinicopathological spectrum of Keratinocytic tumors of skin in a tertiary care centre
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 4
Abstract
Introduction Skin is the largest organ in the body and tumors can arise from any part of the skin Skin cancer represents the most common form of malignant disease in the world1 In India malignant skin tumors constitute about 12 of all cancers National Cancer Registry Programme Indian council of medical research Consolidated report of the Population based cancer registries reported cumulative incidence of skin cancer varying from 05 to 2 per 100000 population2 Non melanoma skin cancers are associated with substantial morbidity including loss of function and disfigurement and their treatment is costly Early diagnosis can reduce morbidity and cost There is a definite role of pathologists in the management of tumorsAim To study the different Clinicopathological features of Keratinocytic skin tumors and analyze the tumors according to age sex site and incidenceMaterials and Methods This is a prospective study from June 2015 to August 2017 for a period of 26 months Excision biopsy specimens and skin punch biopsies sent for histopathological evaluation to the Department of Pathology Dr B R Ambedkar Medical College were studiedResults Out of the 140 skin tumors studied 130 were benign and 10 were malignant Incidence of benign tumors was most common in the younger age groups Premalignant tumors were more common in the 4th decade These tumors showed an overall male preponderance However malignant tumors were found to be more common in females and in the older age groups The sun exposed areas were the most common site of both benign and malignant Keratinocytic tumors Squamous cell carcinoma was found to be more common than Basal cell carcinomaConclusion We studied 140 cases of Keratinocytic tumors of skin 872 were benign 57 were PreMalignant and 71 were malignant Most common benign tumor in our institution was verruca vulgaris and the most common malignant tumor in our institution was squamous cell carcinoma Although malignant tumors were seen in older age group benign tumors showed prevalence in younger patients Our findings mostly correlate with the published Indian literatureKeywords Non melanocytic skin tumors Keratinocytic tumors Keratoacanthoma Bowens disease Premalignant skin tumors
Authors and Affiliations
Tricha Kulhalli, Sujatha R, Manjunatha Y. A
Role of mast cells in surgically resected specimens of appendices
Introduction Mast cells are very closely linked to diseases and have a significant role in inflammatory process The functions of mast cells depends on release of preformed granules The aims and objectives of present stud...
Clinicpathological study of ovarian tumors: A 5 year study
A wide spectrum of neoplasms are encountered in the ovary because of the totipotential and multipotential capacity of ovarian germ cells and mesenchymal cells Ovarian neoplasms are the cause of highest mortality in femal...
A cytological comparison of efficacy of bronchioalveolar lavage, transbronchial needle aspiration and image guided fine needle aspiration for diagnosis of pulmonary lesions in a rural tertiary care centre
Introduction Pulmonary lesions include a wide variety of benign and malignant conditions of lung pleura mediastinum and vertebrae Lung cancer is a frequently diagnosed cancer worldwide1 Although clinical data location an...
Role of thoracoscopic pleural biopsy in evaluation of pleural effusion
Context Evaluation of a patient with pleural effusion involves clinical radiological and cytological evaluation of pleural fluid and histological evaluation of pleural biopsy It is not always possible to identify the exa...
Immunophenotyping in Acute leukemias: First tertiary care centre experience from Punjab
Acute leukemia is a heterogenous group of disorders, require multidiscplinary approach for diagnosis and prognostication. Immmunophenotyping has emerged as important tool in diagnosis of hematolymphoid malignancies. Sinc...