Clinicopathological study of primary small intestine lymphoma
Journal Title: International Journal of Medical and Health Research - Year 2017, Vol 3, Issue 1
Abstract
Primary intestinal lymphoma (PIL) is defined as an extranodal lymphoma arising in the intestine. This study includes 11 PILs. Objectives: The objective of this study was to evaluate the clinicopathological characteristics of primary non‑Hodgkin’s lymphoma (NHL) in the small and large intestine. All cases were reclassified according to the World Health Organization classification of lymphoma in 2001. Immunohistochemistry (IHC) was used to confirm the histopathological diagnosis. Materials and Methods: Eleven cases of primary non‑Hodgkin in the small and large intestine were studied retrospectively in a 5 year period. There were seven cases of resected intestinal specimens and four biopsy specimens. Five cases from ileum and two cases each from caecum and duodenum and one case each from jejunum and duodenum. Hematoxylin and eosin stained sections were studied with light microscopy and IHC for CD5, 20, 21 and cyclin D1 were done. Results: It is a retrospective study of 11 cases of intestinal lymphomas. Abdominal pain and abdominal lump were two main common presenting symptoms. NHLs were more common in the small intestine. PILs are common in adults (75% above 46 years) with male preponderance. All were NHLs and B‑cell type. Five cases were diffuse large B‑cell lymphoma and four cases each were mucosa‑associated lymphatic tissue lymphoma and follicular lymphoma. One case was lymphomatoid polyposis or mantle cell lymphoma. Conclusion: PILs is rare and differs significantly from their gastric counterpart, not only in pathology but also with regard to clinical features, management and prognosis. Due to the lack of characteristic symptoms and a low incidence rate, PIL is misdiagnosed until serious complications occur, such as perforation and bleeding and hence needs to be accurately diagnosed.
Authors and Affiliations
Dr. Ajay Kumar
Keywords
Related Articles
- EP ID EP581951
- DOI -
- Views 144
- Downloads 0
Carcinoid tumors of the appendix-our experience in Garhwal region of Uttarakhand
Objective: To calculate the incidence of incidently discovered carcinoids among all appendisectomy cases and compare the experience with the recent literature on the subject. Material and methods: The medical records of...
A questionnaire based study regarding the knowledge, attitude and practice of self-medication among undergraduate medical students
Introduction: Self-medication is usually defined as intake of any type of drugs for treating oneself without professional supervision to relieve an illness or a condition. Self-medication is a common type of self-care be...
Rapid detection of dengue virus by multiplex real time PCR at SMS medical college & attached Hospitals, Jaipur
Objective: To determine the magnitude of Dengue virus in patients presenting with Dengue like illness (DLI) during the postmonsoon period. Materials and methods: A total of 100 blood samples of patients having DLI, atten...
A prospective randomized double blind study comparing isobaric ropivacaine 0.5% with dexmedetomidine and 0.5% ropivacaine alone in spinal anaesthesia in lower limb and perineal surgeries
Introduction: The versatility of spinal anaesthesia is afforded by a wide range of local anaesthetics and additives that allow control over the level, the time of onset and the duration of spinal anaesthesia. The present...
Studying the relationship between the outlines of the face, maxillary central incisor and maxillary arch in Indian population by Fourier analysis along with spectrophotometric shade analysis of the teeth in different age groups
Purpose: To investigate the quantitative relationships between the outlines of the face, the maxillary central incisor, and the maxillary arch by using Fourier analysis as well as spectrophotometric shade selection in di...