Co-infections; Their Role in HIV Acquisition and Disease Progression
Journal Title: Microbiology Research Journal International - Year 2015, Vol 6, Issue 2
Abstract
HIV/AIDS disease manifestations play critical roles on the host's immune response to infections especially cell-mediated immunity which is central in combating many other infections, allowing opportunistic pathogens that otherwise rarely infect humans, to cause disease. There is paucity of information to satisfactorily explain the geographical pathophysiological overlaps of malnutrition, bacterial, parasitic, and viral infections widespread in sub-Saharan Africa (SSA) where HIV burden is much higher than elsewhere. HIV and/or co-infections may worsen HIV related symptoms and outcomes, alter the presentation or/and increase viral virulence consequently, assisting the infectivity. Hence, co-infections are potential cofactors of HIV transmission in SSA. Most of currently published work often underplays co-infections resulting in misleading statistics and conclusions. A lot of studies have been done assessing single infections in isolation or independently yet in real life practical situation such solitary infections are rare. The prevalence of co-infections, how these in isolation or combination modify or modulate HIV transmission remains poorly described.
Authors and Affiliations
K. Duri, B. Stray-Pedersen, E. Gomo
Keywords
Related Articles
- EP ID EP354881
- DOI 10.9734/BMRJ/2015/13797
- Views 56
- Downloads 0
Enhancing Production of Amino Acids from Bacillus spp. Using Batch and Fed-batch Fermentation Strategies
Aims: Production of amino acids from black strap sugar cane molasses by Bacillus sp. R22EG1 strain and Bacillus sp. R20EG2 using batch and fed-batch (pulsed and continuous feeding) cultures was investigated to achieve th...
Analysis of Amino Acid 530 and 549 of Hemagglutin Gene in Two Canine Distemper Virus Strains
Canine distemper virus (CDV) is prevalent among domestic dogs and causes disease in various types of carnivores worldwide. In the present study, the genotype of two CDV strains, namely, ZJJ-SD and ZJJ-LN, were investigat...
Prevalence and Antimicrobial Susceptibility of Listeria monocytogenes Isolated from Beef, Pork and Chicken Sold in Makurdi Metropolis
Background: The demand for meat and meat products has been on the increase because of its nutritive value. Meat and meat products have been implicated in cases of foodborne diseases in both developed and developing count...
Brucella Prevalence in Goats and Farmers’ Awareness and Practices towards Brucella Infection in Giwa Area of Kaduna State Nigeria
Aims: To detect and determine the prevalence of Brucella antibodies in goats and farmers’ awareness and practices towards Brucella infection in Kaduna State, Nigeria. Experimental Design: A cross sectional study was used...
Cultural Isolation and PCR Based Assay for Detection of flaA gene of Campylobacter jejuni from Acute Diarrheic Patients in Tertiary Care Hospital at Dhaka, Bangladesh
Aim: Among bacterial causes of acute diarrhea Campylobacter species is frequently responsible. Campylobacter spp. is the leading agents of bacterial gastroenteritis in developed as well as developing countries. This stud...