Sero-Prevalence of Cytomegalovirus (IgM) Antibodies among Pregnant Women Attending Ante-natal Clinic at the General Hospital Kafanchan, Kaduna State Nigeria
Journal Title: Microbiology Research Journal International - Year 2015, Vol 9, Issue 5
Abstract
Cytomegalovirus has been implicated as one of the causes of congenital defects in babies of infected mothers. This study was therefore conducted to determine the prevalence of Human Cytomegalovirus IgM antibodies among pregnant women attending antenatal clinic at the General hospital Kafanchan Kaduna State, Nigeria. A total of 190 serum samples were collected and analyzed using Human Cytomegalous Virus Enzymes ImmunoAssay kits. The study revealed that 20 out of the 190 samples were positive for Human Cytomegalous Virus IgM antibodies giving an overall prevalence of 10.5%. The prevalence was found to be higher (50%) in age group 41-45 and lowest (9.2%) in age group 26-30 (χ2 =17.309, P = 0.004). Though not statistically significant the prevalence was higher in multigravid (11.5%) and lower in primigravid (8.3%). More so, women in their third trimester recorded the highest prevalence (12.5%). The high prevalence of Cytomegalovirus antibodies recorded in this study suggests that it could be endemic in the area. There is therefore the need for routine screening of pregnant women and women of child bearing age for cytomegalovirus antibodies. Increased awareness to reduce infection and transmission is also recommended.
Authors and Affiliations
S. Edward Deborah, U. Edward Isaac, O. Nwankiti, B. Shallangwa Ishaku, M. Abdullahi Musa
Keywords
Related Articles
- EP ID EP354621
- DOI 10.9734/BMRJ/2015/16863
- Views 77
- Downloads 0
Serological Characterization and Antimicrobial Sensitivity Profile of Haemophilus influenzae Serotypes Isolated from Aminu Kano Teaching Hospital, Kano, Nigeria
Aim: The aim of this research study was to isolate and serologically characterize Haemophilus influenzae serotypes with view to determine antibiotic susceptibility profile of the isolated bacterium and compare the effect...
Acute Invasive Fungal Rhino-sinusitis: Clinical, Microbiological and Pathological Diagnosis
Background: Acute invasive fungal rhinosinusitis (AIFRS) is a challenging disorder that is diagnosed frequently in immunocompromised patients with very rapid progression. Objective: to estimate the burden of AIFRS in Man...
Linezolid and Methicillin Resistances in S. aureus Isolated from the Anterior Nares of Apparently Healthy Undergraduates of the Niger Delta University, Nigeria
Background: The carriage of Staphylococcus aureus in the anterior nares of subjects in the study environment has not been carried out before and this study is thus a reference study against which future studies can be co...
Evaluation of Antimicrobial Potency and Phytochemical Screening of Persea americana Leaf Extracts against Selected Bacterial and Fungal Isolates of Clinical Importance
Aim: The quest for novel bioactive from natural sources informed the evaluation of the antimicrobial alongside the phytochemical composition of leaf extracts of Persea americana obtained from Akure, Ondo State, Nigeria....
Immobilization and Thermostability of Manganese Peroxidase from Trichoderma harzianum
The aim of the present investigation was to isolate Manganese peroxidase (MnP) (EC 1.11.1.13) from Trichoderma harzianum. The optimal pH and temperature for the enzyme production were 5.0 and 30°C. The best...