Comparative Analysis of Oral Pregablin vs Oral Flupertine as Premedication for Laparoscopic Gall Bladder Surgeries
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 5
Abstract
Background: Cholecystectomy is one of the most common intraabdominal surgical procedures performed in the present era. Acute pain in post-operative period affects patient significantly as it may cause adverse effects. Hence; we planned the present study to assess and compare the effect of oral Pregablin and oral Flupertine given as premedication in patients undergoing Laparoscopic gall bladder surgeries. Materials & Methods: The present investigation included 60 patients scheduled for Laparoscopic surgery under general anesthesia. All the patients were explained about visual analogue scale (VAS) for postoperative pain assessment. ‘0’ means no pain and ‘10’ means maximum pain. On the day of surgery, patients were randomly selected and given either oral Pregablin 150 mg or oral Flupertine 200 mg one hour before surgery. Group P- Received 150 mg Pregablin one hour before surgery, Group F- Received 200 mg Flupertine one hour before surgery. Patient was given i.v. paracetamol and was reversed and extubated. Postoperative pain was assessed by Visual analog score (VAS). All the results were recorded in Microsoft excel sheet and were analyzed by SPSS software. Results: Non- significant results were obtained while comparing the mean hemodynamic parameters in between the two study groups at different intraoperative and postoperative time interval. Higher level of satisfaction was observed among subjects of Pregablin group. However; while comparing the occurrence of nausea among subjects of both the study groups, non-significant results were obtained. Conclusion: More satisfactory results occur when Pregablin is used as a premedication agent in patients undergoing laparoscopic cholecystectomy.
Authors and Affiliations
Mamta Harjai, Shivani Rastogi, Priyesh Bhaskar, Anurag Agarwal
Keywords
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- EP ID EP536850
- DOI 10.21276/ijmrp.2018.4.5.023
- Views 78
- Downloads 0
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