Comparative Antioxidative and Cytotoxic Activity of Extracts of Moringa Oleifera and its Mistletoe
Journal Title: IOSR Journal of Applied Chemistry (IOSR-JAC) - Year 2018, Vol 11, Issue 1
Abstract
This work is aimed to compare the cytotoxic activity of Moringa oleifera and viscum cruciatum (Mistletoe) plants using brine shrimps utility technique. it also compares the anti-oxidative activity of the plants using DPPH radical scavenging assay. 100g of powdered samples were percolated with 96% ethanol. The extracts were macerated with petroleum ether, ethyl acetate and methanol respectively. The petroleum ether fraction of Viscum cruciatum and that of Moringa oleifera showed higher activity to brine shrimp lethality test wit LC50 values of 99.459 and145.684 respectively, while that of methanol fraction of Viscum cruciatum and that of Moringa oleifera showed fair activity to brine shrimp lethality test with LC50 values of 471.220 and 573.893. While, the methanol extract of Viscum cruciatum and that of Moringa oleifera showed higher activity in DPPH radical scavenging assay with IC50 values of 22.482 and 10.857 respectively, while that of crude ethanol extract of Viscum cruciatum and ethyl acetate fraction of Moringa oleifera showed moderate and fair activity to DPPH radical scavenging assay with IC50 values of 263.77 and 582.023 respectively.
Authors and Affiliations
Abdullahi Garba Usman, H. M Ammani, Shamsu. S Bala
Keywords
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- EP ID EP413935
- DOI 10.9790/5736-1101011318.
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