Comparative Assessment of the Effectiveness and Safety of Sertaconazole Cream Versus Terbinafine Cream Versus Luiliconazole Versus Clotrimazolecream in Patients with Tineacruris
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 1
Abstract
Introduction: Dermatophytosis is an infection of keratinized tissues, epidermis and its appendages hair and nails.Topical treatment of dermatophytosis has advantages like targeting the site of infection which minimizes systemic side effects, and enhanced efficacy of treatment. Topical therapy is also considered to improve patient compliance. So to assess the effectiveness and safety of sertaconazole cream versus terbinafine Cream versus luiliconazole versus clotrimazolecream in patients with a form of dermatophytosis i.e.tineacruris (dermatophytosis of groin and adjacent areas). Material and Method: A randomized, open-label, cohort study was performed over a period of 18 months, from January 2014 to June 2015. Results: The study was continued till 30 participants in each group were available for analysis; a study population of 120 participants was achieved. Age group obtained in this study was indeed ranged from 18 years to 50 years. There were 64 (53.3%) males and 56 (46.7%) female participants in this study. The participants were randomized into four study groups: (A) Sertaconazole, (B) Luliconazole, (C) Terbinafine, (D) Clotrimazole. Conclusion: Response to the topical monotherapy with and sertaconazole 2%, luliconazole 1%, terbinafine 1% and clotrimazole 1% cream was safe and well tolerated in the treatment of tineacruris. Treatment with sertaconazole 2% cream and luliconazole 1% cream was early in the onset with tolerable side-effects.
Authors and Affiliations
Sanjay Khare, Rahul Nagar, Burhanuddin Saify
Keywords
Related Articles
- EP ID EP426718
- DOI -
- Views 68
- Downloads 0
To Study the Prevalence of Microalbuniuria in Amyloid Positive and Negative Patients of Rheumatoid Arthritis
Introduction: Rheumatoid arthritis (RA) is a common, chronic, inflammatory, autoimmune disease of unknown etiology affecting approximately 1% of the world population. Current research aimed to study the prevalence of mic...
A Prospective Study Conducted among Second Year Medical Students to Assess the Stress Levels, Identify their Coping Strategies using Brief Cope Method, to Provide Appropriate Guidance to them and to Reassess their Stress Levels
Introduction: High stress levels are prevalent among medical students. Use of appropriate coping strategies is crucial to overcome stress while use of wrong coping techniques could be deleterious and can lead to a viciou...
Application of Computer Software for Objective Evaluation of Changes in Size and Colour of Gingiva after Scaling and Root Planing
Introduction: Gingival inflammation shows redness and swelling as a sign of inflammation. Reduction of gingival inflammation is an indicator of recovery from gingival disease. This study investigated the quantitative ana...
A Randomized Control Trial Comparing Propofol with Midazolam and Fentanyl Combination for Sedation in Gastrointestinal Endoscopies
Introduction: Propofol can be easily titrated and has a rapid recovery profile, thus has revolutionised sedation practices in gastrointestinal (GI) endoscopy. The objective of this study was to compare efficacy and safet...
A Study on Assessing the Etiology and Different Treatment Modalities of Zygomaticomaxillary Complex Fracture
Introduction: Fracture of the zygomatic complex is amongst the most frequent in maxillofacial trauma, due to its prominence which predisposes it to bear the brunt of facial injuries, the pattern of which may vary geograp...