Comparative effectiveness of commonly used drugs in primary open angle glaucoma in Indian eyes
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2017, Vol 3, Issue 1
Abstract
Aim: Objective of this study to compare effectiveness of first line of topical drugs commonly used in POAG and to see the percentage of the IOP lowering effect of different drugs in Indian eyes. Design: This study was conducted in one of the zonal hospital in north India. The study design was a randomized control trial and sample size of 60 patients was included. Methods: We included Randomized controlled trial of three commonly used drugs (Latanoprsot, Timolol, Brimonidine) for established cases of POAG, NTG and Pigmentary Glaucoma. Patients were followed up for 06 months and IOP recording was done in phase manner for four visits. Data were analyzed using SPSS software over 15.0. Results: At the end of six months, Latanoprost eye drops have the highest percentage of reduction (33%), compare to Timolol (27%) and Brimonidine (25%) group. Latanoprost eye drops also have better patient compliance as a once a day regime. Conclusion: All active first line of drugs is effective in lowering intraocular pressure at the end of 06 months. However Latanoprost eye drops has greater IOP reduction compared to Timolol and Latanoprost group. All these drugs can be chosen as a first line of drugs depending upon patient age factor, the degree and type of glaucoma, compliance of drugs, cost and side effect of these drugs.
Authors and Affiliations
Atul Kumar Singh, Hari Kumar, MK Singh
Keywords
Related Articles
- EP ID EP298083
- DOI 10.18231/2395-1451.2017.0006
- Views 83
- Downloads 0
Progression of diabetic retinopathy after cataract extraction with intraocular lens implantation
Aim of the study is to observe the progression of diabetic retinopathy in patients after cataract extraction and placement of intraocular lens implantation Diabetes affects both the anterior as well as the posterior segm...
Combined scleral fixated intraocular lens and strabismus surgery
Aims & Objectives: In the presence of aphakia & strabismus there is dilemma whether to manage the two conditions separately or together. Here we evaluate the result of combined strabismus and scleral fixated intraocular...
Prevalence of dry eye disease in patients on anti-depressants
ntroduction: Dry eye is a complex multifactorial disease which forms a major proportion of ophthalmology out patients. Most of the patients are on chronic medications including psychiatric drugs. So prevalence of dry eye...
A comparative study on pterygium excision and glue free limbal conjunctival autograft with and without suture
Aim: A comparative study on pterygium excision and glue free limbal conjunctival autograft with and without suture. Materials and Methods: 50 patients of primary nasal pterygium attending ophthalmology OPD in Rotary Hosp...
Analysis of retinal nerve fiber layer thickness in cognitive impairment
Introduction Cognitive impairment may be present at birth or can occur later in adulthood Few studies have shown correlation of cognition with retinal nerve fiber layer thickness RNFL The present study was planned to ana...