Comparative Study of Hscrp in Chronic Kidney Disease
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2015, Vol 5, Issue 7
Abstract
BACKGROUND: Chronic kidney disease (CKD) is a global threat to health mainly in developing countries be cause therapy is expensive and lifelong. over 1 million people worldwide are on dialysis or with a functioning gr aft. Early detection of Chronic kidney disease (CKD) and its consequent complications can prevent its grave c omplications . It causes not only significant morbidity but also it causes high mortality. Because of increase in i ncidence of Diabetes mellitus, hypertension, obesity and an aging population there is increase in progression of chronic kidney disease to end stage renal disease (ESRD). . Cardiovascular disease (CVD) is the major cause of mortality in haemodialysis patients and so it has become imperative to have a screening programme at all level s to detect CKD at an early stage and to initiate specific therapy to reduce the progression of renal disease and also the burden of ESRD (1). High sensitive C-Reactive protein (Hs CRP) assay is useful for sensitive detection of inflammatory state (2,3). This study aims at estimating Hs CRP as a marker of inflammation in CKD patients. AIM : To study the variations of High sensitive C-Reactive protein in chronic kidney disease patients MATERIALS AND METHODS: Estimation of High sensitive C-Reactive protein by Turbidimetry method, kit me thod from Biosystems RESULTS: Mean and standard deviation of HsCRP in CKD cases obtained was 26.08 ± 5.73 and in controls was 0.83 ± 0.15mg/L respectively CONCLUSION: The levels of Hs CRP were found to be elevated in patients with CKD compared to control gr oup. There was a significant relationship betw
Authors and Affiliations
Dr. Sumanth kumar . B*, Dr. Shobharani. B
Keywords
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