Formulation of Antiaging Gel from Roselle Calyces Extract
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2017, Vol 7, Issue 12
Abstract
Abstract: Roselle (Hibiscus sabdariffa L.) is known to have many active compounds that function as antioxidants such as flavonoids, polyphenols, and vitamin C. High antioxidant content has a high antiaging effect. This study aims to create a cream dosage form that has antiaging properties with active ingredients roselle calyx ethanolic extract that meets the requirements of physical evaluation, stability evaluation, and has an antiaging activity before and after use. The ethanol extract of roselle calyx is made by maceration. Creams were made with variations of vitamin C concentration of 1% (w/w), and 2.0% (w/w), also roselle calyx ethanolic extract concentration of 0.5% (w/w), 1% (w/w), 1.5% (w/w), and 2.0% (w/w). Antiaging activity test performed by measurement of moisture, evenness, pore, spot, and wrinkle by using skin analyzer tool. The results showed that the antiaging cream of roselle calyx ethanolic extract has a good physical properties and good stability properties for 1 month of storage. All creams have significantly different antiaging activities and depend on the roselle calyx ethanolic extract concentration. The higher concentration of roselle calyx ethanolic extract, the higher antiaging activity. Antiaging activity with a concentration of roselle calyx ethanolic extract had no significant difference with vitamin C.
Authors and Affiliations
Rosemary Hutagaol
Keywords
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