Antimicrobial activity and phytochemical analysis of Calotropis gigantea root, latex extracts.
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2014, Vol 4, Issue 6
Abstract
The root and latex of Calotropis gigantea were screened for its antimicrobial and phytochemical activities. The solvents used for the roots and latex extraction were n-hexane, benzene, acetone, ethanol, aqueous. The extract was tested against infectious disease causing bacterial such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus using the well diffusion method. The aqueous, ethanolic and acetone extract of root of calotropis gigantea inhibition against all the test microbe ranging from 10 mm to 16 mm diameter inhibitory zone. The aqueous and ethanolic extract of latex of calotropis gigantea inhibition against all the test microbe ranging from 10 mm to 18 mm diameter inhibitory zone. In present study, bacterial extract showed a varying zone of inhibition of the growth of tested organism than n-hexane, benzene, ethanol, and aqueous. Phytochemical properties of root and latex of Calotropis gigantea obtain from n- hexane, benzene, acetone, ethanol and aqueous extracts were investigated. The results confirmed that presence of antibacterial activity and phytochemical in the shade dried extract of Calotropis gigantea against the human pathogenic organisms.
Authors and Affiliations
Pramila kori , Prerana alawa
Keywords
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