Comparative study of mast cells in different pathological types of surgically resected appendix specimens
Journal Title: MedPulse -International Medical Journal - Year 2017, Vol 4, Issue 5
Abstract
Mast cells, constantly present in appendix can vary in numbers in normal and pathological states. The objectives are looking for role of mast cells in pathogenesis of appendicitis, their quantitative in normal appendix and appendicitis as well as in different layers of wall of appendix in varied pathological entities and their relationship with eosinophils. One hundred patients were selected and mast cells, eosinophils counted and compared in formalin fixed appendicectomy specimens by H and E, toluidin blue and Van Gieson stains. Females dominated in the study with maximum cases (56%) in the age group of second and third decades. Recurrent appendicitis dominated in the pathological (69%), whereas high eosinophilic count was observed in acute eosinophilic appendicitis and high mast cell count in acute eosinophilic and recurrent appendicitis. A positive correlation with mean eosinophilic and mast cell counts in appendicitis was noted with increasing mast cell count with fibrosis.
Authors and Affiliations
Abhijit Banerjee, Debasis Bhattacharya, Soma Datta, Nikhilesh Dewasi, Jyotirmoy Bhattacharyya
Keywords
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