Comparison between time-domain and spectral-domain OCT in the detection of retinal nerve fiber layer defects in glaucoma patients
Journal Title: Guoji Yanke Zazhi - Year 2018, Vol 18, Issue 5
Abstract
AIM: To compare the use of the instruments' built-in normative databases, the sensitivities of time-domain optical coherence tomography(Stratus OCT)and spectral-domain OCT(Spectralis OCT)in the detection of retinal nerve fiber layer(RNFL)defects in patients with glaucoma.<p>METHODS: Fifty-two eyes of 35 patients with open angle glaucoma were included. A total of 69 hemiretinas with photographically identified RFNL defects were analyzed using the fast RNFL scan of Stratus OCT and the circle scan in Spectralis OCT. The OCT parameters were evaluated at 5% and 1% abnormality levels using the instruments' built-in normative databases. The diagnostic sensitivity of each parameter was compared between the two devices.<p>RESULTS: The Spectralis OCT detected RNFL defects within each quadrant more frequently than the Stratus OCT at both the 5%(79.7% <i>vs</i> 63.8%, <i>P</i>=0.01)and 1%(56.5% <i>vs</i> 40.6%, <i>P</i>=0.01)abnormality levels. At the 1% abnormality level, the sensitivity was significantly higher in the standard sector of Spectralis OCT than in the clock-hour sector of the Stratus OCT(68.1% <i>vs</i> 39.1%, <i>P </i><0.01).<p>CONCLUSIONS: Using the instruments' built-in normative databases, the diagnostic sensitivity of the Spectralis OCT parameters was higher than that of the Stratus OCT parameters for detecting glaucomatous RNFL defects.
Authors and Affiliations
Young Cheol Yoo
Keywords
Related Articles
- EP ID EP564972
- DOI -
- Views 125
- Downloads 0
Effects of double-incision phacoemulsification combined with trabeculectomy on glaucoma with cataract
AIM: To explore the effects of double-incision phacoemulsification combined with trabeculectomy on visual acuity, intraocular pressure and complications in patients with glaucoma complicated with cataract. <p>METHODS: Th...
IL-6, IL-8 and TNF-α expression levels in serum and aqueous humor in patients with neovascular glaucoma and their significance
AIM: To detect IL-6, IL-8 and TNF-α expression levels in serum and aqueous humor of patients with neovascular glaucoma(NVG)and explore the significance. <p>METHODS:A prospective case analysis method was applied to includ...
Curative effect of Ranibizumab combined with laser photocoagulation for proliferative diabetic retinopathy
AIM:To investigate the clinical efficacy of Ranibizumab combined with laser photocoagulation in the treatment of proliferative diabetic retinopathy(PDR). <p>METHODS: Totally 80 patients(101 eyes)with PDR admitted to our...
Research and application of RNA interference in cataract
RNA interference(RNAi)is the post-transcriptional gene silencing based on sequence-specific degradation of mRNA, and triggered by double-stranded RNA.RNAi technology is widely used in gene therapy and research of gene fu...
Study on risk factors of diabetic retinopathy in type 2 diabetic patients
AIM:To investigate the risk factors of diabetic retinopathy in type 2 diabetic patients. <p>METHODS: The data of 1 013 patients with type 2 diabetes mellitus who admitted to hospital from January 2013 to April 2017 were...