Comparison of Anaesthetic Efficacy of Dexmedetomidine with Bupivacaine Versus Fentanyl with Bupivacaine for Spinal Anaesthesia
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: Spinal anaesthesia is defined as “the regional anaesthesia obtained by blocking nerves in subarachnoid space”, is a popular and common technique. Traditionally amide and ester linked local anaesthetics have been used in regional anaesthetic techniques, and bupivacaine has emerged as the most commonly used drug for spinal anaesthesia. This study is designed to compare the effect of dexmedetomidine with bupivacaine versus fentanyl with bupivacaine for spinal anaesthesia in lower abdominal and lower limb surgeries. Materials and Methods: The study was conducted amongst subjects undergoing elective lower abdominal and lower limb surgeries under spinal anaesthesia in Mahatma Gandhi hospital, Jaipur. The study population was randomly divided into 2 groups with 45 patients in each group. Group BD received 0.5% hyperbaric bupivacaine 12.5mg + 5μg dexmedetomidine and Group BF received 0.5% hyperbaric bupivacaine 12.5mg + 25 μg fentanyl. Qualitative data was analyzed by chi-square test. Quantitative data was analyzed by student ‘t’ test. Results: A total of 90 subjects were enrolled with 61 males and 29 females. Majority of subjects were between 31-40 years of age. The mean onset in Group BD was 12.04+/- 1.79 with the upper bound interval 12.5 and lower bound interval 11.5. The mean duration in Group BD was 150.2+/- 13.7 with the upper bound interval 154.3 and lower bound interval 146.06. In 2 patients of Group BD and 3 patients of Group BF it was till T6. In 2 patients of Group BD and 3 patients of Group BF it was till T7. Conclusion: The mean time of onset of both sensory and motor analgesia was less in group BD as compared to group BF, although not statistically significant. The duration of motor blockade was almost similar in both the groups.
Authors and Affiliations
Anit Kumar Kajala, Prakash Gupta, D. D. Jethava, Priyambada Gupta, Durga Jethava
Keywords
Related Articles
- EP ID EP531166
- DOI 10.21276/ijmrp.2018.4.1.125
- Views 73
- Downloads 0
Flow Cytometric Immunophenotyping of Acute Leukaemia in Adult and Its Comparison with Cytomorphology
Background: Immunophenotyping has become an inseparable tool for precise characterization of acute leukemia (AL), which is the corner stone of therapeutic success in these cases. There is paucity of data regarding immuno...
Bacteriological Profile and Antibiotic Sensitivity of Organisms Isolated From Neonatal Sepsis at Tertiary Care Hospital
Introduction: As neonatal septicaemia is a life threatening emergency and delays in diagnosis and treatment with appropriate antibiotics may have devastating consequences, surveillance is needed for an ongoing review of...
A Comparative Study of Microscopic Detection Methods and Haematological Changes in Malaria
Objective: To find out the relative incidence of different species of Plasmodium, most sensitive method for detection and various hematological changes in Malaria. Methods: In 6 months study, blood sample were collected...
Retrospective Evaluation of Imaging Findings in Patients with CNS Lesions: An Observational Study
Background: Central nervous system (CNS) pathologies are a significant cause of mortality and morbidity world-wide. Frequently, structural neuroimaging exams (brain computed tomography (CT) and magnetic resonance imaging...
Study of CD4 Count Level in HIV-TB Co-Infection in ART Patients Before And After Anti-Tubercular Treatment
Introduction: HIV and TB co-infection is when people have both HIV infection and also active TB disease. HIV infected individuals have a high risk of developing active TB following infection and also have increased morta...