Comparison of cardiac autonomic neuropathy in asymptomatic T2DM and normal individuals
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2016, Vol 3, Issue 4
Abstract
Introduction: The availability of simple, non-invasive tests for cardiovascular autonomic function has supported an extensive clinical and epidemiologic evolution in the investigation of Cardiac autonomic neuropathy. Such data forms a strong body of evidence in detecting and monitoring impaired autonomic function in patients with diabetes. The proposed study aims at detecting the presence of autonomic neuropathy in an early and possibly stills a reversible phase in Type 2 Diabetes Mellitus (T2DM) individuals in comparison to non T2DM normal individuals. Material and Methods: The cross sectional case control study consisted of 200 subjects, 100 as Cases with T2DM in the age group 35 to 50 years and 100 age and sex matched normal subjects without T2DM as Controls. Resting heart rate, Sinus Arrhythmia and Valsalva Ratio were measured from ECG recorded. Based on these heart rate tests they were grouped into normal, early and definite autonomic neuropathy changes. An informed written consent to participate in the study was taken from the subjects. There was no financial burden on the subjects. The study protocol was approved by the Institutional Ethical Committee. All the quantitative data were summarized and statistically analysed.
Authors and Affiliations
Thejaswini KO, Dayananda G
Keywords
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