Comparison of dexmeditomidine and magnesium sulfate as adjuvants to lidocaine for intravenous regional anaesthesia for prolongation of duration of analgesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 8, Issue 3
Abstract
Background and Objectives: Intravenous regional anaesthesia (IVRA) is a very effective block for forearm and hand surgeries, but its effectiveness is limited by its short duration of action. Dexmeditomidine and magnesium sulfate have found to prolong the action of local anaesthetics through a peripheral mechanism. Our study compares the efficacy of two different types of adjuvants to lidocaine when used in IVRA for prevention of tourniquet pain and to increase the duration of postoperative analgesia.Methods: This is a prospective, randomized, double-blinded study. Sixty patients scheduled for hand or forearm surgery were randomly divided into two groups, comprising 30 patients each. Group D received 40 ml of 0.5% lidocaine + 1 µg/kg of dexmeditomidine and Group M received 40 ml of 0.5% lidocaine + 2 ml of 50% magnesium sulfate through the cannula on operative arm. The onset and recovery times of sensory and motor blocks, time to tourniquet pain, postoperative VAS score, time to first rescue analgesic and haemodynaµg parameters were recorded. Results: There was no statistically significant difference observed between the two groups with respect to sensory and motor block onset and regression times as well as intraoperative analgesic requirements (P ≥ 0.05). However, dexmedetomidine showed more favourable haemodynaµg variables, increased tourniquet tolerance time and prolonged duration of postoperative analgesia as compared to magnesium sulfate (P ≤ 0.05).Conclusion: Dexmedetomidine is a better adjuvant to lidocaine than magnesium sulfate for IVRA with respect to tourniquet tolerance, postoperative analgesia and haemodynaµg stability in the postoperative period.
Authors and Affiliations
Basappa M Diwanmal, Prashant A Lomate
Keywords
Related Articles
- EP ID EP453355
- DOI 10.26611/10158311
- Views 148
- Downloads 0
Comparison of surgical field - sevoflurane versus propofol based anaesthesia in functional endoscopic sinus surgery
Background: Functional endoscopic sinus surgery requires a bloodless surgical field in order to facilitate the ease and thoroughness of the surgery to produce good surgical results without complication. Aim: To ompare se...
A prospective randomized double-blinded study comparing intrathecal nalbuphine vs intrathecal fentanyl added to 0.5% hyperbaric bupivacaine for perioperative anaesthesia and postoperative analgesia in patients undergoing hernioplasty
Background- Various adjuvants are added to the local anesthetics intrathecally, to prolongate the duration of anesthesia. Among the adjuvants the most commonly preferred are the opioids. Opioids like fentanyl, morphine,...
Comparison of laryngeal mask airway Proseal and I-gel in patients posted for elective surgeries under general anaesthesia
Background: In spite of tremendous advances in contemporary anesthesia practice, airway management continues to be of paramount importance to the anesthesiologist. Hemodynamic changes are the major undesirable consequenc...
Study of spinal anaesthesia in paediatric age group in rural set-up
Background: The commonly adopted method of anaesthesia in children is general anaesthesia (GA) as per the traditional standards. But, in rural set up, where there is lack of finance, high tech monitoring equipment, man p...
Preemptive analgesia in patients undergoing infraumbilical laparotomy under spinal anesthesia: A randomized, double-blind, comparative evaluation of varying doses of oral pregabalin
Background:Pain is the foremost complaint in majority of patients following surgery. Eventhough, several studies have reported the effectiveness of preemptive pregabalin, its optimal dose for reducing acute post-operativ...