Comparison of effects of hyperbaric bupivacaine with or without dexmedetomidine use in subarachnoid block
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 1
Abstract
Background: The primary aim of intrathecal local anaesthetic is to provide adequate sensory and motor block necessary for all below umbilical surgeries. A number of adjuvants, such as clonidine, midazolam and others have been studied to prolong the effect of spinal anaesthesia. Dexmedetomidine, a substance that has been used for sedation and analgesia in veterinary medicine for many years is under evaluation as a neuraxial adjuvant. Aim and Objectives: To study Effects of use of hyperbaric Bupivacaine with or without Dexmedetomidine for subarachnoid block in relation to various anaesthetic parameters Material and Methods: It was prospective, randomized, double blind study conducted at tertiary care centre over a period extending from January 2014 to October 2015. The study included a total of 100 patients divided into two groups (each of 50 patients) i.e. control and study groups depending upon drugs administered. Results: The regression of sensory block was slower and onset of motor block is quicker in patients those who received intrathecaldexmedetomidine. There was a significantly prolonged duration of sensory analgesia also, the onset as well as time for attaining maximum sensory level was significantly faster in study group. Summary and Conclusions: Subarachnoid block using 0.5% hyperbaric Bupivacaine (15mg) with dexmedetomidine (5mcg) leads to significantly quicker onset and prolonged duration of action of Motor and Sensory block also a minimal intraoperative and postoperative complication as compared to 0.5% hyperbaric bupivacaine.
Authors and Affiliations
Nitinkumar Ingle, Vaibhav Mahankale, Deepak Kokane, Satish G Deshpande
Keywords
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