Comparison of Hemodynamic Changes amongst Subjects Using Prophylactic Ephedrine v/s. Phenylephrine Intramuscularly for Prevention of Hypotension in Elective Caesarean Section Under Subarachnoid Block
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 3
Abstract
Background: Spinal anesthesia has evolved in recent years as a simple, effective, and acceptable technique for providing anesthesia in various surgical procedures. Various prophylactic and rescue regimens have been advocated for treatment and prevention of hypotension. The usual approach adopted is to treat the hypotension that has developed during caesarean section. With the aim to compare two commonly used vasopressors, ephedrine and phenylephrine, this study was performed with pre-emptive use of these vasopressors to prevent hypotension after spinal anesthesia for caesarean section. Materials and Methods: The present study was conducted in a prospective observational manner at tertiary care teaching institute from central India. Subjects above 18 years scheduled elective caesarean section were included in the study. Subjects with any contraindications to spinal anesthesia were excluded from the study. After which monitoring was done every 3 minutes for the next 10 minutes and then every 10 minutes till the surgery lasted. All the data was arranged in a tabulated form and analyzed using SPSS software. Students t test was used for comparing mean of two samples. P value < 0.05 was considered significant at 95% confidence interval. Results: The present study was conducted amongst 90 females with 30 subjects in each group. The mean age in group C, Group E and group P was 25.63 years, 26.10 years and 26.63 years respectively. The mean pulse rate in Group C, Group E and Group P at 0 minutes was 89.80±13.076, 86.07±12.443 and 88.93±11.744 respectively. The mean arterial pressure in Group C, Group E and Group P at 0 minutes was 90.00±7.931, 88.87±7.705 and 90.37±7.600 respectively. The mean arterial pressure in Group C, Group E and Group P at 1 minutes was 86.77±7.846, 88.07±10.667 and 89.03±8.954 respectively. The mean arterial pressure in Group C, Group E and Group P at 3 minutes was 80.63±11.272, 82.97±11.763 and 83.93±9.425 respectively. Conclusion: Hypotension is eminent in patients undergoing spinal anesthesia for caesarean section. Various approaches devised for prevention and treatment including use of vasopressors.
Authors and Affiliations
Sumita Bhargav, Himanshu Nandwani, Anjali Bhure, Sayli Kulkarni, Arihant Jain, Yasha Tiwari
Keywords
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- EP ID EP531426
- DOI 10.21276/ijmrp.2018.4.3.006
- Views 71
- Downloads 0
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