Comparison of intracuff air, lignocaine, lignocaine with sodium bicarbonate and ketamine for attenuating post operative sore throat
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 3, Issue 1
Background and Aims: Tracheal intubation is a foremost cause of trauma to the airway mucosa, resulting in postoperative sore throat (POST) with reported incidence of 21 – 65%.Various pharmacological methods have been used for attenuating POST like topical lignocaine, inflation of endotracheal tube (ETT) cuff with lignocaine, lignocaine with sodium bicarbonate and preoperative ketamine gargle etc. We conducted a study to compare the incidence and severity of POST when intracuff ketamine is used and compared with intracuff air, lignocaine and lignocaine with sodium bicarbonate. Materials and Methods: A randomised study with 100 patients divided into 4 groups of 25 each was done. After intubation, the endotracheal tube cuff was inflated with either air (Group A), 2% lignocaine with normal saline (Group L), 2% lignocaine with 7.5% sodium bicarbonate (Group B) or ketamine with normal saline (Group K) and study parameters like Sore throat with incidence/severity (Mild, Moderate, Severe) and hemodynamics at extubation, TUBE tolerance, hoarseness, dysphagia, postoperative nausea vomiting and cough were observed. The results were tabulated and compared statistically. Results: The incidence and severity of POST was reduced in all groups compared to group A. Tube tolerance was better in Group K, but with slight increase in arterial blood pressure at extubation. Inflation of endotracheal tube cuff with lignocaine, lignocaine with sodium bicarbonate and ketamine can reduce the incidence and severity of POST. The best results are seen with lignocaine with sodium bicarbonate and ketamine, with minimal side effects. Conclusion: Intracuff Ketamine could be a better alternative to gargle in reducing POST and needs further trial
Authors and Affiliations
Rashmi N R, Shashidhar G S, Balabhaskar S, Kiranchand N
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How To Cite
Rashmi N R, Shashidhar G S, Balabhaskar S, Kiranchand N (2017). Comparison of intracuff air, lignocaine, lignocaine with sodium bicarbonate and ketamine for attenuating post operative sore throat. Medpulse International Journal of Anesthesiology, 3(1), 5-9. https://europub.co.uk/articles/-A-260402