Comparison of serum level of zinc and magnesium in healthy subjects and patients with diabetes and metabolic syndrome and its association with insulin resistance in individuals aged over 10 in Ahvaz, Khuzestan Province, Iran
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 8
Abstract
Many studies suggest the fluctuation of the serum level of zinc and magnesium in diabetic patients compared with healthy individuals and etiological role of these elements in the pathogenesis of diabetes. This study aimed to measure the serum level of zinc and magnesium in three groups of healthy individuals, patients with diabetes, and patients with metabolic syndrome and relationship of these elements with insulin resistance in Ahvaz population. In this cross-sectional descriptive-analytic study 150 person (50 healthy, 50 with diabetes, and 50 with metabolic syndrome) evaluated. For each participant questionnaire filled out including demographic information, blood pressure waist circumference, height measured and blood sampling. The collected data were analyzed using t-test, ANOVA, and Chi-square by SPSS 17 software at a significance level of 0.05. in results in this study Study findings showed that there is a significant relationship between zinc and magnesium serum levels in all groups. Also, a significant inverse relationship was observed between zinc level and insulin resistance in patients with diabetes and also magnesium level and FBS, zinc level and BMI, and magnesium and BMI in all three groups (P<0.05). In conclusion given the low levels of zinc and magnesium in diabetic patients, it is recommended that such people include foods rich in zinc and magnesium in their daily diet. Keywords: Zinc; Magnesium, Patients with diabetes, metabolic syndrome, Insulin resistance.
Authors and Affiliations
Alireza Jahanshahi, Hajieh Shahbazian, Homeira Rashidi, Leila Hardani Pasand, Majid Karandish, Akram Ahangarpour, Seyed Mahmoud Latifi
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