Comparison of two different doses of injection esmolol on haemodynamic response and seizure duration during electroconvulsive therapy
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 5
Abstract
Introduction-This study was aimed to compare the effects of two different doses of injection esmolol on haemodynamic response during ECT. Also the effects of esmolol pre-treatment on seizure duration, duration of anaesthesia and duration of recovery from anaesthesia and adverse effects if any were observed. Methods -Total 40 patients of ASA I or II posted for ECT were each studied thrice during three consecutive ECT treatments. Hence total of 120 ECT exposures studied. Three groups were formed Group P received placebo; Group E1 and E2 received intravenous esmolol 12.5mg and 25 mg bolus before ECT. Heart rate (HR), systolic and diastolic blood pressure (SBP/DBP) was recorded pre-bolus and every minute for 5 min and then 10, 15, 20, 25 & 40 minutes post-bolus. Duration of seizure, duration of anaesthesia, recovery and incidence of side effects were noted. Results- HR, SBP and DBP increased significantly in placebo group; at 5 minutes post ECT, HR in P, E1 and E2 group was (mean 145.20 ± 18.67,128.98 ± 17.72, 121.75 ± 18.38); SBP was (mean 168.85 ± 10.29, 152.88 ± 14.16, 143.90 ± 12.91) and DBP was (mean 114.45 ± 6.52, 103.35 ± 8.45, 93.05 ± 9.34) Superior hemodynamic stability was found in E2. Duration of seizure (P=0.952), duration of anaesthesia (P=0.437) and recovery (P= 0.792) had no effect of esmolol pre-treatment. No side effects were found in any of the study groups. Conclusion- Esmolol 25mg pre-treatment has stable haemodynamic results and no effect on seizure duration thus therapeutic outcome of ECT is not affected.
Authors and Affiliations
Dr. Vaijayanti Nitin Gadre
Keywords
Related Articles
- EP ID EP506541
- DOI -
- Views 116
- Downloads 0
Prevalence and Antimicrobial Resistance Pattern of Bacterial Isolates in a Tertiary Care Hospital of Assam, India
Background: Antimicrobial resistance (AMR) has emerged as a major public health problem all over the world. Infections caused by resistant microbes fail to respond to treatment, resulting in prolonged illness and greater...
Association of ABO and Rhesus Blood Group with Type-2 Diabetes Mellitus in Northern India: A Cross-Sectional Study
The phenotypic "ABO" blood groups are inherited antigenic substances which are found on the surface of red blood cells in addition to other tissues. ABO & Rhesus (Rh) blood groups systems besides being most important in...
Anxiety Disorder in Patients with Essential Tremor
Background: Essential tremors is one of the most common movement disorder and is a classic example of disorder whose interpretation is shifted from one dimensional disease with prominent motor feature to a multidimension...
Fake Journals, spurious published papers and bogus impact factors: Need for an overhaul and transparency for an academic perspective
Background Since over the last more than several decades there has been mushrooming growth of journals and/or publication agencies which mimic the peer-reviewed scientific journals. This article entails the fabrication o...
Disseminated cutaneous Leishmaniasis in a patient who is HIV positive with a flare up as iris -a case report
There is a broad spectrum of clinical manifestations of cutaneous leishmaniasis. The usual lesion is a small, red papule which over several weeks becomes darker, crusts in the centre and eventually ulcerates & heals, lea...