Continous Hyper-Frationated Accelerated Radiotherapy (CHART) In Head And Neck Cancers
Journal Title: National Journal of Medical and Dental Research - Year 2018, Vol 6, Issue 4
Abstract
• Background – head and neck malignancies are moderately radiosensitive. With the aim to increase loco-regional control Continuous Hyper-fractionated Accelerated radiotherapy has been studied in 50 patients with head and neck malignancies. • Patient and methods – 50 patients diagnosed with head and neck malignancies participated in the study between July 1996 – March 1997. Average age was 50 (30 – 70 yrs). 82 % male patients and 18 % female patients. Cancer of cheek, alveolar margin, tongue and tonsillar fossa accounts for 96 % of patients. Daily dose of 1.4 Gy thrice daily in 6 hours interval were given for 12 consecutive days. • Results - follow up period 5 months – 15 months, primary site -80 % had shown complete response while 20 % have shown partial response for primary site. Nodal disease – 70 % had shown complete response and 30 % had shown partial response. None of the patient had shown disease progression. Acute radiation reaction - 14 %, 68 % and 18% had shown grade 0, I, II grade acute radiation reaction, no grade III reaction have been observed in study group. Reoccurrence – 8 % at primary site, 12 % had shown nodal recurrence. • Conclusion – CHART has shown better loco-regional control. It could be more effective in early stage disease. Acute radiation reaction is significant but manageable. Treatment volume has to be kept minimal to reduce radiation reaction.
Authors and Affiliations
Ashutosh Agnihotri, Deepa Agnihotri
Keywords
Related Articles
- EP ID EP574540
- DOI -
- Views 106
- Downloads 0
Histopathology Study Of Extra-Pulmonary Tuberculosis In Different Age, Sex And Various Organ Distributions
Background:In this paper, We study,“Histopathologicalstudy of Extra pulmonary tuberculosis”. In different age, sex and various organ distribution. Material and Method:Biopsy samples received in 10% neutral buffered form...
Continous Hyper-Frationated Accelerated Radiotherapy (CHART) In Head And Neck Cancers
• Background – head and neck malignancies are moderately radiosensitive. With the aim to increase loco-regional control Continuous Hyper-fractionated Accelerated radiotherapy has been studied in 50 patients with head and...
A Study To Find Out Clinical Profile Of Cholilithiasis
Introduction: presence of the stone or stones in gall bladder is known as cholilithiasis. It may be asymptomatic to symptomatic. Have multiple presentation. Affects both sexes. It is a major cause of histopathological...
Fractures Of The Radius And Ulna In Adults: An Analysis Of Factors Affecting Outcome
Concurrent data were collected by the authors for fractures of the shafts of the radius and ulna in 90 adult patients to determine the relationshipof subjective, objective, radiographic and economic outcome parameters to...
Study Of Menstrual Hygienic Practices And Reproductive Tract Infection Among The Adolescents Girls
Introduction:Puberty, which is considered as the time of change for the adolescents, is a challenge for young girls because of menstruation. Though it is a natural phenomenon and girls are exposed to very little knowledg...