Correlation of 24-hour urinary protein, urinary protein: Creatinine ratio and HBA1c in type 2 diabetes with and without nephropathy
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 3, Issue 2
Abstract
Background: The leading cause of morbidity and premature mortality in diabetics is nephropathy. closely associated with renal involvement in diabetes. Objectives: To estimate serum levels of HbA1c, 24 ratio in Type 2 diabetics with and without nephropathy. urinary protein and HbA1c levels in these groups. department of Biochemistry, Owaisi Hospital, from October 2016 to May 2017 on 103 diabetes patients comprising of 41 diabetics without ephropathy (Group A) and 62 Type 2 diabetes subjects with nephropathy (Group B) parameters were estimated: Fasting blood glucose, Serum creatinine, HbA1c Results show that the mean values of fasting blood protein to creatinine ratio are significantly increased in Group B when compared to Group A and these parameters are further increased in diabetic subjects with P: C ratio protein: creatinine ratio levels are significantly increased (p< 0.001) with proteinuria more than the physiological range (P: C ratio 0.2) than within physiologicalrange (P: C < positively with high gnificance.HbA1c levels correlated positively with both P:C ratio and 24 levels. Conclusion: This study suggests estimating HbA1c as an indicator of gl method for early diagnosis and intervention for diabetic nephropathy.
Authors and Affiliations
S Mohammed, F Nazki
Keywords
Related Articles
- EP ID EP258559
- DOI -
- Views 287
- Downloads 0
Prevalence of cervical cancer and role of screening programmes by PAP smears
Background: Among the Indian women cervical cancer is the most common genital tract cancer. It is estimated that in India 126,000 new cases of cervical cancer occur annually. Pap test not only plays a crucial role in det...
A study of fasting insulin level among obese and non-obese patients at tertiary health care centre
Background: Obesity has become one of the major health problems in advanced society. It has been proved that obesity is a risk factor for a number of chronic disorders such as cardiovascular diseases, Non-insulin depende...
Prevalence of Lp(a) in diabetes and normal population
Background: Lipoprotein a-Lp(a) has similar structure of LDL except it has one more Apo-A protein. It is produced in liver and it is highly atherogenic. Lp(a) is usually genetically predisposed but seemed to have associa...
Serum fasting lipid profile and lipoprotein(a) in northern keralite patients with myocardial infarction
Coronary artery disease isrising as a major health problem in Kerala. The presentstudy was aimed to verify whether there is increase in the concentration of Lipoprotein (a) [Lp(a)] and fasting serum lipid profile in Nort...
Urinary NGAL as an early marker of renal injury in Type II diabetics
Background: Microalbuminuria is a reversible stage of renal dysfunction in Diabetic patients and it’s detection allows early intervention thus checking its progress to ESRD. However, Microalbuminuria is transient and may...