CORRELATION OF HbA1c, LIPID PROFILE AND FASTING BLOOD SUGAR AND DURATION OF DIABETES MELLITUS WITH SEVERITY OF DIABETIC RETINOPATHY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 30
Abstract
BACKGROUND We have studied patients having diabetic retinopathy attending the Department of Ophthalmology, Katuri Medical College, Guntur in a cross-sectional, hospital-based, non-interventional study. Aim- To study the prevalence of different parameters like duration of diabetes mellitus, fasting blood sugar at the time of diagnosis of retinopathy, HbA1c, lipid profile and correlate with severity of diabetic retinopathy and assess the statistical significance. Objective- To identify the important factors that can influence severity of Diabetic retinopathy in our area, in order to identify highrisk patients early, to prevent visual loss. MATERIALS AND METHODS The present study is a hospital-based cross-sectional study, which was conducted at our tertiary care centre. We have studied a total of 302 patients diagnosed to have diabetic retinopathy for one and a half years in our tertiary care centre. RESULTS Among the 302 patients taken into the study, 64% were females and 36% were males. Diabetic retinopathy predominantly occurred in patients above 50 years of age. HDL < 40 mg%, LDL > 100 mg% and VLDL > 40 mg% levels have significant correlation with different grades of retinopathy. This also denotes that these values are related to the severity of diabetic retinopathy. Glycosylated haemoglobin (HbA1c) above 7%, serum total cholesterol > 200 mg%, serum total triglycerides > 200 mg% and duration of diabetes mellitus > 9 years did not correlate with the severity of diabetic retinopathy. CONCLUSION HDL < 40 mg%, LDL > 100 mg% and VLDL > 40 mg% levels have significant correlation with different grades of retinopathy. This also denotes that these values are related to the severity of diabetic retinopathy with chi-square test with p-value of < 0.05. HbA1c values and high fasting blood sugar did not correlate with severity of retinopathy
Authors and Affiliations
Nagasree D. V. C. , Ramakrishna Rachakonda
Keywords
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- EP ID EP538858
- DOI 10.14260/jemds/2018/767
- Views 61
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