CORRELATION OF TOTAL LEUCOCYTE COUNT, EOSINOPHIL, NEUTROPHIL AND LYMPHOCYTE COUNTS WITH PULMONARY FUNCTION IN COPD PATIENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 84
Abstract
BACKGROUND Chronic obstructive pulmonary disease (COPD) is the fourth leading cause of death in India. In COPD, there is an increased number of leucocytes, suggesting a role for the inflammatory response in the clinical progression of the disease. The aim of the study is to evaluate the degree of pulmonary function impairment by pulmonary function tests and to correlate leucocyte counts with pulmonary function tests in COPD patients. MATERIALS AND METHODS This descriptive study was carried out among 30 COPD volunteers (patients) referred from Pulmonology Department of Saveetha Hospital. The pulmonary function test was done by using a computerised spirometer and complete blood cell count was also made for all the subjects. Pulmonary parameters (FEV1 and PEFR) recorded were correlated with blood parameters (TLC, neutrophils, eosinophils, lymphocytes). RESULTS There was strong negative significant correlation observed between FEV1 and TLC, absolute neutrophil count, absolute eosinophil count whereas there exists a weak negative significant correlation between FEV1 and absolute lymphocyte count ( p<0.05). CONCLUSION The findings indicated that whenever the blood parameters (TLC, neutrophils, eosinophils and lymphocytes) increase there was a decrease in the pulmonary parameters in COPD patients.
Authors and Affiliations
Sureshbalaji R. A, Prem Kumar S, Lavanya R, Krishna Kumar S, Sivapriya D. V, Ramaswamy C, Shyamala Thirumeni
Keywords
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- EP ID EP276833
- DOI 10.14260/jemds/2017/1275
- Views 106
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