Molecular mechanisms regulating metastasis of cancer cells with special emphasis on rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a malignant tumor of soft tissue derived from embryonic mesenchymal and/or neuroectodermal tissues. It is most often associated with other genetic syndromes such as Li-Fraumeni or Bechwith-Wiede...

Role of leptin in the regulation of lipid and carbohydrate metabolism

Leptin is a hormone secreted primarily by adipose tissue and its blood levels depend on the amount of fat stored in adipocytes. Leptin has a wide range of physiological effects. Acting directly or through the sympathetic...

The role of genetic and environmental factors in the etiology of esophageal atresia and tracheo-esophageal fistula

Esophageal atresia and tracheo-esophageal fistula are severe congenital malformations, whose etiology is still poorly understood. So far, numerous genetic and environmental factors that may contribute to the occurrence o...

Białka szoku termicznego w reumatoidalnym zapaleniu stawów: przyjaciel czy wróg?

Reumatoidalne zapalenie stawów (RZS) jest jedną z najczęściej występujących chorób reumatycznych na świecie. RZS to uciążliwa, progresywna oraz wciąż nieuleczalna układowa choroba tkanki łącznej o podłożu autoimmunizac...

Stężenie karnityny w osoczu po przewlekłym zatruciu alkoholem