DENDRIMER: A COMPLETE DRUG CARRIER
Journal Title: Int J of Pharm Rev& Res - Year 2011, Vol 1, Issue 1
Abstract
Dendrimers are a new class of polymeric materials. They are highly branched, monodisperse macromolecules.As a result of their unique behaviour; dendrimer is suitable for a wide range of biomedical and industrial applications. The unique architecture design of dendrimers, high degree of branching, multivalency, globular architecture and well defined molecular weight distinguishes there structures as unique and optimum nanocarriers in medical applications, such as drug delivery, gene transfection, tumor therapy, diagnostics etc. Micro/Nanoparticle drug-delivery system is the popular one and able to increase the selectivity and stability of therapeutic agents. The bioactive agents can be easily encapsulated into the interior of dendrimers (or) chemically attached i.e. conjugated or physically absorbed onto the dendrimer surface, serving the desire props of the carrier to the specific needs of the active material and its therapeutic applications. In addition to supplying a multivalent backbone for drug attachment dendrimers also provide access to various new polymer architecture that are potentially relevant to drug delivery applications
Authors and Affiliations
B. Pavan Kumar , I. SarathChandiran , B. Bhavya , Sravanthi. U , Sindhuri. M
Keywords
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