Descriptive study of tuberculosis trend at a tertiary care centre in Marathwada region
Journal Title: Medpulse International Journal of Medicine - Year 2018, Vol 6, Issue 2
Abstract
Background: India accounts for the highest proportion of global burden of disease with around one-fifth (21%) of the global incidence of the disease contributed by India. It is supposed that the number of new tuberculosis cases detected by the positive sputum for acid-fast bacilli represent just more than fifty percent of the existing TB cases. There are reports from studies done in India which show a high percentage of sputum-negative pulmonary tuberculosis as well as extrapulmonary tuberculosis cases. The present study describes the tuberculosis trends in terms of sputum-positive and sputum-negative pulmonary tuberculosis and the proportion of extrapulmonary tuberculosis cases at a tertiary care centre in Aurangabad district of Maharashtra from the year 2010 to 2016. Methods: It is a retrospective study. Study duration was from 2010 to 2016. Patients were diagnosed as having tuberculosis with help of clinical examination, microbiological, radiological tests as per records and sputum was mentioned as positive or negative based on Ziehl Nelson staining for acid-fast bacilli. Records were analysed to describe the tuberculosis trends in terms of sputumpositive and sputum-negative pulmonary tuberculosis and the proportion of extra-pulmonary tuberculosis cases. Sites of extrapulmonary tuberculosis were described. Results: Total 6209 patients were analysed. Out of this, 3537 patients (56.97%) were having pulmonary TB and 2672 patients (43.03%) were having extrapulmonary TB. Pulmonary tuberculosis (3537 patients) was either sputum-positive (2435 patients, 68.84%) or sputum-negative (1102 patients, 31.16%) based on Ziehl -Nelson staining method. Extra pulmonary tuberculosis (2672 patients) was contributed by lymph node tuberculosis (766 patients, 28.67%), abdominal tuberculosis (570 patients, 21.33%), pleural effusion (687 patients, 25.71%), bone tuberculosis (139 patients, 5.20%), TB meningitis (248 patients, 9.28%), other rare sites of tuberculosis like breast, ophthalmological TB (262 patients, 9.81%). Conclusions: There was a high proportion of sputum-negative pulmonary TB as well as extrapulmonary TB cases.
Authors and Affiliations
Avinash Ramrao Lamb, Vijaykumar Ramappa Kapse
Keywords
Related Articles
- EP ID EP361177
- DOI -
- Views 65
- Downloads 0
A prospective randomized study comparing the impact of twice divided versus once daily prednisolone dosing on hyperglycemia and glycemic variability among renal transplant patients
Aim: Prednisolone exerts high glycemic variability leading to endothelial dysfunction and coronary events. This study compares glycemic excursions, hypothalamic–pituitary–adrenal axis suppression, sleep disturbance, lipi...
Atypical Presentations of Malaria with Age and Seasonal Variations
Background: Malaria is a seasonal disease in most parts of India, the maximum prevalence is from June to November.In endemic regions, malaria can present with unusual features due to development of immunity, increasing r...
A study of various demographic distribution among valvular lesions in the patients with rheumatic heart disease
Background: Although once considered a rarity in the Indian subcontinent, the prevalence of rheumatic heart disease (RHD) is now recognized to be very high, particularly among children and young adults Aims and Objective...
A cross sectional follow-up study of kidney donors in a tertiary care centre from south India
Background: Living renal donors form the major pool of kidney transplantation in India. Even though many studies have demonstrated the safety of living renal donation there is always a concern about safety of renal donor...
A study of mixed connective tissue disorders at the department of medicine of a tertiary health care centre
Background: The concept of mixed connective tissue disease (MCTD) as a separate immune-mediated connective tissue disease (CTD) was first introduced by Gordon C. Sharp and coworkers > 40 years ago, but there is still no...