Abstract

The objective of this research was to design and evaluate site specific Periodontal strips containing Moxifloxacin hydrochloride (MH) in a biocompatible carriers which has excellent activity against wide range of microorganisms. To prepare MH periodontal films by using natural biocompatible polymer (Basil seed gum etc). BSG was extracted from Basil seeds. This will be used in preparation of periodontal strips. FT‐IR has performed to reveal no interaction between MH, ISG and other excipients. The method choosen for preparation of periodontal strips is solvent casting technique. The prepared strips has to be evaluated for their thickness uniformity, folding endurance, weight uniformity, content uniformity, surface pH, and in-vitro antibacterial activity. In-vitro release from periodontal films has to fit to different equations and kinetic models like zero order, first‐order equations and Hixson‐Crowell, Higuchi models and korsmeyer peppas model to reveal drug release kinetics. A short‐term stability study has to be performed to study the whether their will be decline in drug content or any changes in dosage form

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