Design and In-vitro Evaluation of Fast Dissolving tablet of Urapidil Hydrochloride
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2015, Vol 3, Issue 4
Abstract
An attempt has taken to formulate Urapidil Fast Dissolving tablet using various super disintegrants such as Cross povidone, Cross carmellose sodium and Sodium starch glycolate employing direct compression technique. Mannitol was added in the formulation to promote the cooling sensation of the prepared tablet. The physiochemical and micromeritic parameter were evaluated and all the formulations showed satisfactory result. The release characteristic was evaluated by dissolution study. Result showed the formulation containing Cross povidone exhibited faster release than all formulation. Drug polymer interaction study was conducted by FTIR and DSC. No such major interaction was found for the formulation
Formulation and Evaluation of Domperidone Fast Dissolving Film by Using Different Polymers
The present study deals with the investigation carried out on developing a fast dissolving delivery system releasing Domperidone concomitantly in stomach for treating vomiting and motion sickness. Domperidone FDOF was pr...
Assessment of Electrical Heart Axis: Comparison of Hexaxial Reference System with Unipolar and Bipolar Lead Based Formula
Introduction: The assessment of electrical heart axis (EHA) has important applications towards interpretation of electrocardiogram (ECG) of patients in both clinical and epidemiological studies. Objective: The present st...
Thermal Sintering Technique: A Novel Strategy Used in the Design of Gastro Retentive Floating Matrix Tablets of Nicardipine HCl and Its Evaluation
Exploration of sintering technique in the pharmaceutical sciences is relatively recent. The aim of the present study was to prepare thermally sintered floating matrix tablets of Nicardipine HCL (NIC) and to study the eff...
Microfloral Studies in Rhizosphere of Plant Cassia Angustifolia Vahl Grown in Different Soil Treatments
The present study was carried out on the isolation, quantitative and qualitative analysis of microflora from the rhizosphere soils of Cassia angustifolia. The plants were grown in pot culture experiments with three treat...
Food Safety among Food Vendors in Chennai City-A Cross Sectional Survey
Background: Every year, the World Health Organization selects a priority area of global public health concern as the theme for World Health Day, which falls on 7 April, the birthday of the Organization. The theme for Wor...