DESIGN DEVELOPMENT AND EVALUATION OF MODIFIED RELEASE TABLET OF MONTELUKAST SODIUM
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 1
Abstract
The purpose of this research was to prepare a modified release tablet of montelukast sodium. Montelukast sodium is Leukotriene antagonist which is rapidly absorbed after the oral administration. At first the drug was spray dried, the complex obtained was mixed with the other excipient and tablets were compressed using 10 station tablet rotary press. The compressed tablets were coated with different coating polymer like HP 50, HP 55 and Eudragit S. The tablets were evaluated for drug release by carrying out the dissolution and UV spectroscopy.
Authors and Affiliations
Krunal Patel
Keywords
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