Development solid dosage forms – suppositories with ambrosia and study their physico-chemical and technological properties
Journal Title: Фармацевтичний журнал - Year 2014, Vol 2, Issue 2
Abstract
The study of technological properties of suppositories with ambrosia. It is shown how to affect the solubility of active substances and the size of their molecules for therapeutic activity. The structural and mechanical properties of lipophilic and hydrophilic bases produced by classical methods to further study the optimal composition of the media. Analyzed and selected the optimal composition of suppository bases. We describe the chemical composition and solubility properties imunostymulyuchi cerago bee. Also dose cerago bee in suppositories, which is selected according to the results of previous studies of the drug Vinibis C (Production "per minute +" state. кegistry. № 77.99.23.3.U. 7738.9.08 from 10.09.2008 year). Confirmed choice of solid dosage forms – suppositories as rational dosage form that will provide optimal pharmacological effect of drugs and determine their properties. The research on choosing bases of suppositories with ambrosia bee for optimum uniformity of dosage and distribution of active ingredients in the dosage form.
Authors and Affiliations
B. Т. Kudryk, O. I. Tikhonov
Keywords
Related Articles
- EP ID EP587554
- DOI -
- Views 52
- Downloads 0
Clinical and economic analysis of medicinal prescriptions for children and adolescents with Helicobacter pylori-associated gastroduodenal pathology
The significant prevalence of chronic gastritis and/or duodenitis among children and adolescents, the ability of H. pylori to induce serious complications lead to the importance of effective anti-helicobacter therapy. T...
Synthesis and antiexudative activityof pyrolin derivatives 2 - ((4-amino-5- (furan-2-yl)-1,2,4-triazol-4H-3-il)-sulfanil)-N-acetamides
The continuous research of new effective drugs is associated with a significant number of diseases, pathological conditions. Conventional treatment with existing drugs could be ineffective, or addictive, and have a large...
Application of surface in physics methods in pharmaceutical development of the medicine on the basis of essential phospholipids
The main issues addressed in the process of pharmaceutical medicine’s development include the choice of substance, excipients; development of technological and analytical methods of control; definition of critical points...
Synthesis and physicochemical properties 4-((R))amino)-5-methyl-4H-1,2,4-triazole-3-thiols
Purposeful synthesis of derivatives of 1,2,4-triazole is one of the most important branches of modern pharmaceutical science Modern pharmaceutical market of domestic medicines requires constant updates of existing range...
Development of laboratory technology of the ointment Allergolik
Today quite important and urgent task of modern medicine and pharmacy is expanding the range of herbal medicines for the treatment of dermatitis with secondary fungal skin lesions. The objective of the work is developme...