Dexmedetomidine as epidural adjuvant to Ropivacaine in elective lower limb surgeries
Journal Title: Medpulse International Journal of Anesthesiology - Year 2017, Vol 8, Issue 1
Abstract
Epidural adjuvants are used to prolong the action of local anesthetic agent so as to have prolongation of motor and sensory block. Dexmedetomidine a newer α2 agonistic agent with predominant affinity to α2receptor, α2:α1 affinity is 1600:1.Ropivacaine an amide local anesthetic agents.Which is an ‘S’ isomer of the propyl analogue of Mepivacaine and Bupivacaine with long acting potential. Pharmacologically it has similar properties to Bupivacaine, but with lesser cardiotoxicity profile. In our study we divided 40 patients posted for elective lower limb surgeries into two group of 20 patients each. Patients in Group R received total of (150 mg) 20ml of 0.75% Inj.Ropivacaine with 1 ml of Normal saline epidurally. Patients in Group RD received total of (150 mg) 20ml of 0.75% Inj.Ropivacaine with 1 ml of 1 microgram per kg of Inj.Dexmedetomidine and saline to make up volume of 1 ccepidurally. We compared the onset of motor and sensory block; duration of motor block and post-operative analgesia, two segment regression time and sedation scores of both the groups. From our study we found that not only the onset of sensory and motor blockade were hastened in Group RD but also, duration of motor block, duration of post-operative analgesia were prolonged. Sedation scores were higher in Group RD and two segment regression was prolonged in Group RD.
Authors and Affiliations
Darshan MS, Sri Devi S, G M Sanjeev
Keywords
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- EP ID EP440405
- DOI 10.26611/1015811
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