Diagnosis of breast lesions by FNAC and its comparison with histopathological diagnosis - Two years study
Journal Title: Medpulse International Journal of Pathology - Year 2019, Vol 9, Issue 2
Abstract
Background: Breast lesions are one of the commonest clinical presentations in surgical OPDs. Breast malignancies are one of the commonest malignant lesions in females and the incidence rate is nowadays increasing. FNAC is a well accepted tool to diagnose any breast lesion. Aims: To study the cytological features of breast lesion and to compare FNAC diagnosis with histopathological diagnosis, to decide sensitivity and specificity of FNAC diagnosis of breast lesions. Materials and Methodology: The present study carried out in Pathology Department at P.D.U. Medical College, Rajkot was a two-year study comprising of 180 cases of FNAC breast, for which specimens were later on received. The FNAC diagnoses were classified into various types of lesions and were compared to histopathological diagnosis. Results: In present study, total 180 cases were studied on cytology in which 120 cases were benign and 59 cases were malignant. All cases were confirmed on histopathology except 03 cases. Fibroadenoma was common benign lesion and Infiltrating ductal carcinoma NOS variant was the commonest malignant lesion. Sensitivity, specificity and accuracy of FNAC were 95%, 100% and 98.3% respectively. The positive predictive value and negative predictive value of FNAC were 100% and 97.6% respectively. Conclusion: FNAC is safe, rapid, economical and highly accurate method of investigation in case of breast lump preoperatively which helps avoiding undue surgery and inconvenience of biopsy. High specificity and high negative predictive value for malignancy suggest that FNAC differentiate between benign and malignant lesions very well.
Authors and Affiliations
Amita B Chavda, Shilpa H Gandhi, Gauravi A Dhruva
Keywords
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- EP ID EP536542
- DOI 10.26611/105927
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