Diagnosis of Myocardial Infarction by Biomarkers-A Review
Journal Title: Scholars Academic Journal of Pharmacy - Year 2017, Vol 6, Issue 10
Abstract
Cardiovascular diseases are major causes for morbidity and mortality worldwide, among this myocardial infarction is one of them. Myocardial infarction can be diagnosed by physical examination of the patient, electrocardiogram, angiography and biomarkers. Since 40 years, cardiac biomarkers were extensively using for diagnosis of cardiac abnormalities. AST was the first biomarker used in year 1954. Myoglobin, Creatinine kinase, Troponin, lactate dehydrogenase were established biomarkers and Myeloperoxidase, Copeptin, Growth differentiation factor (GDR-15), Heart type fatty acid-binding protein (H-FABP),B-type natri-uretic peptide(BNP) and N-terminal fragement of pro-BNP, High sensitive C-reactive protein (hs-CRO), Placental growth factor (PIGF), Whole blood choline(WBCHO) and plasma choline, Pentraxin 3(PTX-3), Pregnancy associated plasma protein A(PAPPA), Soluble cluster of differentiation 40 ligand, Ischemia modified albumin(IMA) were emerging biomarkers. In this review we mainly focused in the diagnostic and prognostic information of various biomarkers used for diagnosis of myocardial infarction. Keywords:Cardiovascular diseases, myocardial infarction, diagnosis, biomarkers.
Authors and Affiliations
G. Gnaneswar, B. Sudha Chandra, P. Priyanka, C. Gopinath
Keywords
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