Diagnostic discrepancies in fine needle aspiration diagnosis of parotid gland lesions in a resource limited hilly region
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
The characteristic cytological features of parotid gland lesions have been well described in literatures but there also exist cytological diagnostic pitfalls that make it difficult to form an accurate diagnosis in some cases Aim To evaluate the sensitivity specificity along with positive predictive value negative predictive value by Cyto histological correlation in various lesions with an emphasis on discordant cases Materials and Methods A retroprospective study of 250 non guidedpalpable FNAC of suspected parotid gland enlargements were performed from 2006 to 2018 at tertiary care hospital The cytological smears were stained with May grunwald giemsa papanicolaou hematoxylin eosin stains Surgically resected specimens were received for histopathology in 103 relevant cases only The cytologic and Histologic slides were studied compared and correlated where ever possible and statistical analysis done Result Out of 250 patients male to female ratio was 14 1 The different categories of salivary gland lesions included non neoplastic benign and malignant constituted 109108 and 33 cases respectively Pleomorphic adenoma and mucoepidermoid carcinoma was the commonest benign and malignant neoplasm reported in this study respectively False negative and false positive results were mainly due to cystic and papillary lesions The sensitivity specificity along with positive predictive value negative predictive value and diagnostic accuracy of present study was 6842 9880 9285 9325 and9320 respectively Conclusion Though palpable FNAC of the parotid gland tumors is simple rapid and costeffective in a developing country but rate of characterization of specific type of parotid gland tumor is lower due to overlapping cytomorphologyKeywords Parotid swelling Histopathology Cytology Morphological discordancenbsp
Authors and Affiliations
Binay Kumar, Usha Joshi, Bhawana Pant, Deepa Arya
Keywords
Related Articles
- EP ID EP475491
- DOI 10.18231/2394-6792.2018.0042
- Views 58
- Downloads 0
Evaluation of prothrombin time, international normalized ratio and platelet counts among women presenting with vaginal bleeding in first trimester of pregnancy
Introduction: Pregnancy is associated with substantial changes in the tissue factor pathway and in the hemostatic system.(1) It is also characterised by impressive changes in the activating and inhibitory pathways of coa...
HER 2/neu as a theranostic marker in colorectal carcinoma and its relationship with histopathological correlates-A pilot study
Introduction: Colorectal carcinoma(CRC) is one among the many leading causes of cancer related mortality worldwide. The survival rate of patients with CRC is better because of advancements made in the treatment modalitie...
Efficacy of cell block immunocytochemistry in the diagnostic workup of non hodgkin lymphoma-experience from a tertiary care hospital in North India
The WHO 2016 update on lymphoid neoplasms incorporates criteria independent of tissue architecture in the diagnosis and subclassification of nonHodgkin lymphoma Thus lymphoid neoplasms with characteristic immunophenotype...
Spectrum of tumour and tumour-like lesions of bone in a Tertiary Care Hospital in North Karnataka, India
Introduction The wide spectrum of bone tumours their diverse origin and the tendency of these tumors to produce overlapping anatomic patterns make osseous neoplasms a complicated but highly challenging area from the poin...
Placental pathology in low birth weight babies a prospective observational study
Introduction Low birth weight LBW babies are more common in developing countries like India The placenta is an organ which connects fetus to mother during intrauterine life Any change in the mother reflects on placenta a...