Differential Diagnosis of Anemia from Bone Marrow Aspiration Cytology: A Prospective Study of 100 Consecutive Cases
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 3
Abstract
Introduction: Anemia is a common clinical problem requiring the precise diagnosis of underlying etiology in order to provide effective therapy. Measurement of red cell indices along with peripheral smear examination is done in most of the cases of anemia to establish the type and possible reasons, but these tests are inconclusive for some cases and they may need bone marrow examination. So this study has been done to emphasize the role of bone marrow aspiration (BMA) cytology in establishing the definite diagnosis of anemia. Materials and Methods: This is a prospective study that has been conducted for bone marrow examination on 100 cases with anemia. BMA was done and the smears were stained using leishman’s stain and some special stains such as myeloperoxidase stain, pearls stain, Periodic acid-Schiffs in selected cases. Trephine biopsy was done in 14 cases for further evaluation. Results: We have included 100 consecutive cases of anemia, which had undergone BMA for various indications. Most common symptom was prolonged fever. Haemoglobin level was estimated for each patient. Pancytopenia was the commonest indication for marrow examination. Hypoplastic anemia was found in21% of cases, which was the most common bone marrow examination finding, followed by haematological malignancies , that was found in 18% of cases. Conclusion: BMA was an important tool that helps to reach the underlying etiology of anemia and also to know the response to treatment without using any costly instrument in a lesser time. So Bone marrow examination should be performed in anemic patient for whom the first line investigations are inconclusive.
Authors and Affiliations
Pradeep Kumar Behera, Chandraprava Mishra, Ajit Prasad Mishra, Subhasini Nayak, Akhyaya Kumar Dash
Keywords
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- EP ID EP531378
- DOI 10.21276/ijmrp.2018.4.3.002
- Views 86
- Downloads 0
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