Digoxin Toxicity presented with Right Bundle Branch Block: A Case report of Drug- Drug Interaction
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 10
Abstract
Digoxin, one of the digitalis glycosides has specific effects on the myocardium. The effects of Digoxin in heart failure are mediated by its positive inotropic and neurohormonal deactivating effects, whereas the effects of the drug in atrial arrhythmias are related to its vagomimetic actions. It is the most common drug used in treatment of congestive heart failure and tachy-arrhythmias. It is used in treatment of arrhythmias but when arrhythmias occur in a patient on maintenance dose of Digoxin, its toxicity should be suspected. Here we report a case of Digoxin toxicity with the therapeutic dose confirmed by elevated Serum Digoxin levels. This occurrence could be due to Digoxin itself or this adverse effect could be predisposed by a suspected drug –dug interaction (SDDI) with the concomitant drugs this patient was prescribed.
Authors and Affiliations
Shreya R Patel, Harsha D Makwana, Kamlesh P Patel, Supriya D Malhotra, Pankaj R Patel
Keywords
Related Articles
- EP ID EP276382
- DOI 10.17511/ijmrr. 2017.i10.08
- Views 163
- Downloads 0
Adrenal cysts-a report of four cases including one with bilateral involvement
Adrenal cystic lesions are rare entities. Four types of cystic lesions of the adrenal gland have been described in literature namely, epithelial cysts, endothelial cysts, pseudocysts and parasitic cysts. Tumors of the ad...
Dengue serology–role of NS1 antigen: evaluation and future prospect
Introduction: According to the estimates, nearly 70% of the disease burden occurs in Asia and is on constant rise. Dengue virus infection has emerged as a major public health concern across the globe in terms of mortalit...
Cytogenetics abnormalities in acute leukemias of ambiguous lineage: First report of complex variant philadelphia translocations
Background: Acute leukemias of ambiguous lineage (ALAL) are incompletely characterized and are very rare, accounts< 4% of acute leukemias . In most leukaemias the cytogenetic and molecular genetic changes have emerged to...
Interrelation between birth weight, body mass index, insulin resistance, C-Reactive Protein-hs, adiponectin and leptin in children (Age 10 to 20 years)
Background: India is projected to have one of the largest populations of obese children over the next decade. Birth weight reflects maternal nutrition and fetal programming which may be a leading cause of obesity. Adipok...
A comparative study on the efficacy of first vs second blood culture set in the diagnosis of bacteraemia in Central Referral Hospital, Sikkim, India
Background: An important but controversial subject is the number of blood culture sets required for the diagnosis of blood stream infection (BSI) and also the use of appropriate antibiotics to treat bacteremia. This pape...