Digoxin Toxicity presented with Right Bundle Branch Block: A Case report of Drug- Drug Interaction
Journal Title: International Journal of Medical Research and Review - Year 2017, Vol 5, Issue 10
Abstract
Digoxin, one of the digitalis glycosides has specific effects on the myocardium. The effects of Digoxin in heart failure are mediated by its positive inotropic and neurohormonal deactivating effects, whereas the effects of the drug in atrial arrhythmias are related to its vagomimetic actions. It is the most common drug used in treatment of congestive heart failure and tachy-arrhythmias. It is used in treatment of arrhythmias but when arrhythmias occur in a patient on maintenance dose of Digoxin, its toxicity should be suspected. Here we report a case of Digoxin toxicity with the therapeutic dose confirmed by elevated Serum Digoxin levels. This occurrence could be due to Digoxin itself or this adverse effect could be predisposed by a suspected drug –dug interaction (SDDI) with the concomitant drugs this patient was prescribed.
Authors and Affiliations
Shreya R Patel, Harsha D Makwana, Kamlesh P Patel, Supriya D Malhotra, Pankaj R Patel
Keywords
Related Articles
- EP ID EP276382
- DOI 10.17511/ijmrr. 2017.i10.08
- Views 168
- Downloads 0
To compare the outcome of intramedullary nailing and locking compression plate fixation in treatment of proximal one third tibia fracture: A randomized control trial
Background: Fractures of tibia shaft are most common of long bone fractures. Proximal tibia fractures account for approximately 5% to 11% of all tibial injuries and affect knee function and stability in most of the cases...
A case report on and chronic calcific pancreatitis primary systemic amyloidosis with symptomatic gastric involvement
Systemic amyloidosis is a disorder characterized by extracellular deposition ofamyloid in various organs and tissues including the gastrointestinal tract, kidney, heart, and liver.Gastric involvement occurs in 8–12% of p...
Clinicopathological Study of Meningioma
Background: Meningiomas are tumours originating from meningothelial cells. They are commonly located at intracranial, intraspinal or occasionally ectopic site. They show histological diversity and are categorized into th...
A study of Antenatal risk factors and fetal outcome in IUGR pregnancies
Introduction: Low birth weight (LBW) (neonate weighing <2500 g) is a multifactorial phenomenon.Many maternal and fetal factors are found significantly to be associated with the low birthweight. Material and Methods: It w...
Methotrexate Induced Toxic Epidermal Necrolysis: A Case Report
Methotrexate continues to be one of the most widely used systemic immunosuppressive agents in dermatology. We describe a case of low-dose methotrexate (MTX) toxicity in a patient with chronic plaque psoriasis occurring d...