DNA microarray, types and its application in medicine
Journal Title: Scholars Academic Journal of Biosciences - Year 2015, Vol 3, Issue 7
Abstract
Abstract: The rapid growth in the field of biochemistry and organic semiconductors to produce microchips, which began a new movement in the production of DNA and gene chips were chips. There are many types of biological microchip technology are ongoing. The generation of DNA, RNA, proteins and living cells are used in biological microchip. So far for the study of the properties, activities and the role of genes and proteins and molecular processes within cells and tissues mostly of a gene discovery and gene or protein is the maximum number of individual studies that include a variety of methods use in PCR and markers, blotting (Western blotting, Northern blotting and Southern blotting) and other techniques. Microarray technology allows the expression of thousands of genes simultaneously is little monitoring. From its origins to the present, a number of databases, software and technology that has been developed in the update. This article discusses the basics of each of the technologies and applications and how to analyze it pays Microarray explains. Keywords: Microarray, gene expression, cDNA array, an oligonucleotide array.
Authors and Affiliations
Khadijeh Dadkhah, Seyed Hossein Mosavi Anijdan, Masoumeh Karimi, Mahboubeh Khadem Abolfazli, Fatemeh Rezaei, Fereshteh Adel, Gholamreza Ataei
Keywords
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