Dr. PI POLYPHENOL CONTENT, PHYTOCHEMISTRY COMPOSITIONS AND ANTIOXIDANT ACTIVITY OF DIFFERENT EXTRACTS FROM MARINE SPONGE AAPTOS SUBERITOIDES GROWN IN NHATRANG BAY, VIETNAM
Journal Title: International Journal of Pharmacy and Pharmaceutical Sciences - Year 2019, Vol 11, Issue 9
Abstract
Objective: To investigate the content and antioxidant activities of polyphenol, the correlation between polyphenol content and their antioxidant activities, and phytochemistry compositions of different extracts from marine sponge Aaptos suberitoides commonly found growing in Nhatrang bay, Vietnam orienting application into functional food and pharmacy. Methods: Evaluating the toxicity of antioxidant polyphenol powder preparing from the initial concentrated extract was by the adjusted Behrens Karber method and a correlation between polyphenol content and antioxidant activities basing on the Pearson coefficient in Excel. Separating antioxidant polyphenol content was base on solvents polarization of n-hexane, chloroform, ethanol, ethyl acetate and n-butanol which the quantification of polyphenol content and antioxidant activities, and preliminary phytochemical compositions qualitative. Results: Antioxidant polyphenol powder did not affect mice weight during the assay time of 28 d. Polyphenol content and antioxidant activities got the highest value at chloroform extract in comparison to other extracts, a significant difference (p<0.05) and strong correlation (R2>0.9). Polyphenol content (122.682 mg gallic acid equivalent ml-1), total antioxidant activity (368.183 mg ascorbic acid equivalent ml-1), reducing power activity (24.08 mg FeSO4 equivalent ml-1) and DPPH scavenging (72.48±1.54 %) were the highest values. Alkaloids, flavonoids, steroids, tannins and triterpenoids existed in initial methanol extract. Weakly polarized polyphenol content was 70.27% in comparison to initial methanol extract. Conclusion: Antioxidant polyphenol of sponge Aaptos suberitoides has the potential for application into the field of functional food and pharmaceuticals.
Authors and Affiliations
DANG XUAN CUONG, VU NGOC BOI, TRAN KHAC TRI NHAN, DINH HUU DONG, THAI MINH QUANG, PHAM THI KIM TRAM, DANG THI THANH TUYEN
Keywords
Related Articles
- EP ID EP624902
- DOI 10.22159/ijpps.2019v11i9.34003
- Views 71
- Downloads 0
FORMULATION AND EVALUATION OF DASATINIB LOADED SOLID LIPID NANOPARTICLES
Objective: The aim of present work was to formulate and evaluate Dasatinib (DST) loaded solid lipid nanoparticles (SLNs) as a potential anticancer drug delivery system by enhancing its solubility.Methods: SLNs consist of...
ENCAPSULATION OF ZIDOVUDINE IN DIFFERENT CELLULOSIC ACRYLIC AND METHACRYLIC POLYMERS LOADED MICROSPHERES: IN VITRO CHARACTERIZATION AND COMPATIBILITY STUDIES
Objective: The attempt of the present study was to improve bioavailability and dissolution rate along with reduction in dosing frequency of Zidovudine from microspheres.Methods: In this study an effort was taken to devis...
ESSENTIAL OIL COMPOSITION OF ARTEMISIA VULGARIS GROWN IN EGYPT
Objective: The objective of this research was to evaluate the significance of the plant's origin and to assess the essential oil composition of Artemisia vulgaris grown in Egypt simultaneously evaluating the effect of en...
SCREENING OF ANTIOXIDANT ACTIVITIES AND THEIR BIOAVAILABILITY OF TROPICAL FRUIT BYPRODUCTS FROM INDONESIA
Objective: The objectives of this study were to investigate the antioxidant activities in peel and seed of six tropical fruits from Indonesia and to evaluate their bioavailability by in vitro digestion model.Methods: Six...
COMPARISON OF THE CYTOTOXIC EFFECTS OF UMBELLIPRENIN AND AURAPTENE
Umbelliprenin and auraptene structurally belong to the class of coumarins. Umbelliprenin can be synthesized chemically or extracted by maceration at room temperature. Various biological effects for both umbel lip renin a...