DRUG UTILIZATION EVALUATION AND ASSESSMENT OF ECONOMIC BURDEN OF ANTICOAGULANTS IN A TERTIARY CARE HOSPITAL IN SOUTH INDIA
Journal Title: Journal of Pharmaceutical and Scientific Innovation - Year 2018, Vol 7, Issue 5
Abstract
Anticoagulants used for many indications, both prophylaxis and therapeutic treatment, are associated with high risk, hence drug utilization evaluation is essential. Objective: The objectives of the study were to evaluate the drug utilization of anticoagulants, assessment of anticoagulant cost in the prescription, identify and assess drug interactions with the use of anticoagulants.Method: This is a 6 months, prospective cross sectional study, evaluating 263 patients for their prescriptions containing anticoagulants in a tertiary care hospital in south India.Results: During the study period, among anticoagulants prescribed, Heparin is found most commonly prescribed for treatment as well as prophylaxis mainly in the cardiology and neurology wards. Acenocoumarol was the second most prescribed anticoagulant followed by Dalteparin Warfarin and Rivaroxaban. Intravenous heparin was prescribed in majority of inpatients of all the departments followed by Acenocoumarol and Enoxaparin. Only few Patients from departments other than cardiology and neurology are prescribed with Enoxaparin, Dalteparin Warfarin and Rivaroxaban. In the discharge prescriptions, Acenocoumarol and Enoxaparin weremainly observed. Among all the prescriptions, 7 cases are found to be prescribed with anticoagulants without any indication, which may increase treatment cost burden on patients. Dose adjustment for lower molecular weight heparin for patients with renal impairment was observed in the present hospital. But the monitoring parameters PT, PTT &INR are performed only in few patients. Moderate drug interactions are found in the prescriptions withmainly heparin and Acenocoumarol.
Authors and Affiliations
Vineela Chadalavada, Venkata Naga Mounika Gangula, Vasa Veera Venkata Saikiran, Gonela Sai Medha Sree
Keywords
Related Articles
- EP ID EP631505
- DOI 10.7897/2277-4572.075106
- Views 68
- Downloads 0
ROLE OF NARINGIN ONGEMCITABINE-INDUCED LIPID PEROXIDATION
Aim: The aim of the present study was to investigate the antiperoxidative property of naringin on gemcitabine-induced lipid peroxidation. Methods: The in vitrowork was carried out usinggoat liver as model lipid source. T...
TECHNICAL SHEET OF FRESH BARK OF THE “WHITE VARIETY” OF BYTTNERIA CATALPIFOLIA, A WILD PLANT CONSUMED IN THE WESTERN PART OF CÔTE D’IVOIRE
Byttneria catalpifolia is one of the most widely consumed wild species, especially those in the mountainous western part of Côte d’Ivoire. The aim of this study was to assess the nutritive potential of dried bark powder...
CHITOSAN AS A COATING AGENT ON THE DRUG ELUTING STENTS TO PREVENT BIOFILM FORMATION DURING STENT IMPLANTATION
Arteriosclerosis is the build-up of fatty cells and tissues within blood vessels. Coronary stents implantation is considered as a common method for atherosclerosis cases. Formation of neointimal tissue and high infection...
A REVIEW ON VISHAVAIDYA JYOTSNIKA
Agada Tantra is one among the eight branches of Ayurveda. Apart from samhitas (classical texts), there are many text books dealing with agada tantra (toxicology) written in various regional Indian languages. Some of them...
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF DEFERIPRONE
Selective and precise RP-HPLC method was developed for estimation of Deferiprone in pure form. Acetonitrile: 0.1% formic acid (70: 30 v/v) was used as optimized mobile phase during the method development at 280 nm. Reten...