Effect of Cell Free Culture Filtrate of Probiotic Isolates on the Growth of Pathogenic Isolates
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2016, Vol 11, Issue 3
Abstract
The emergence of drug resistant strain is a recurrent problem in clinical practice. The incidence of infections due to organisms resistant to β -lactam agents due to production of various enzymes has increased in recent years. The enteric flora comprise large number of cells in the human body and are capable of eliciting immune responses while also protecting against microbial pathogens. Probiotics have very high potential in terms of their antimicrobial activity against antibiotic-resistant enteric pathogens. They have been shown to have wide range of health beneficiary properties. The presence and dominance of Lactobacillus in the vagina is associated with a reduced risk of bacterial vaginosis and urinary tract infections. The primary objective of this work is to study antibiotic resistant pattern of probiotic isolates against β lactam group of drugs. Further study involves effectiveness of cell free culture filtrate of probiotic isolates against β lactamase producing bacteria. Antimicrobial activity is one of the most important selection criteria for probiotics. Bacteriocin and other inhibitory compound might be produced by probiotics has potent action against pathogens. So it can be taken as a supportive supplement along with antibiotics.
Authors and Affiliations
Shivangi Bhatt, Archana Rana, Neepa Pandhi3
Keywords
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