Effect of different sampling locations on the antibacterial property of Centella asiatica leaves
Journal Title: International Journal of Pharmacy and Analytical Research - Year 2014, Vol 3, Issue 3
Abstract
An experiment was carried out to determine the effect of antibacterial activity of Centella asiatica herb collected from different sampling location. The effect can be determined by analysing the bacterial response towards plant extracts. The tested bacterial strains were Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Salmonella typhi. Zone of inhibition produced by different extracts against the selected strains was measured and compared with standard antibiotic penicillin (10μg) and gentamicin (10μg). The result demonstrated that the Centella asiatica from urban area have higher antimicrobial activities (average of 1.629 cm zone of inhibition) than sub-urban (average of 1.305 cm zone of inhibition). All the extracts showed better results against the Escherichia coli strains comparing with penicillin (10μg) but not for gentamicin (10μg) test on the other bacteria strains. The results obtained in the present study suggest that the different extracts of Centella asiatica revealed a significant scope to develop a novel broad spectrum of antibacterial herbal formulations.
Authors and Affiliations
Rasha Saad
Keywords
Related Articles
- EP ID EP656139
- DOI -
- Views 52
- Downloads 0
Evaluate the Disinfectant Activity of Some Commercial Preparations by Rideal -Walker Test.
The aim of this study was to evaluate and compare practically achieved disinfection efficacy of some locally available disinfectants on surfaces and infectious microbiological hospital waste. Three disinfectants were tes...
Method development and validation for the simultaneous estimation of ambroxol Hcl and loratadine in a pharmaceutical formulation by RP-HPLC method
An isocratic Simultaneous estimation by RP-HPLC Method were developed and validated for the quantification of Ambroxol HCl and Loratadine in tablet dosage form. Quantification was achieved by using a reversed-phase C18 c...
Analytical method development and validation of Glimepiride in bulk and tablet dosage form using UV Spectrophotometer
The main objective of the study is to develop and validate an analytical method for quantitative determination of Glimepiride in bulk and tablet dosage form using UV-Visible Spectroscopy. The Glimepiride shows maximum ab...
Design and characterization of nizatidine effervescent floating matrix tablets employing semisynthetic rate-retarding polymers
Nizatidine effervescent controlled release floating tablets employing three grades of HPMC K4M, HPMC K15M and HPMC K100M in four ratios (1:0.5; 1:1; 1:5 and 1:2) were prepared and evaluated. FTIR, DSC and XRD studies on...
Synthesis, antiviral and cytotoxicity activities of N-Sulphonamidomethyl benztriazole derivatives
A series of novel N-sulphonamido methyl benztriazole derivatives had been synthesized by combining benztriazole, formaldehyde and sulphonamides. Structure of synthesized compounds was elucidated by spectral analysis. Syn...