Effect of hypocaloric diet and home based exercises in improving fertility in polycystic ovarian syndrome patients
Journal Title: Medpulse International Journal of Gynaecology - Year 2017, Vol 3, Issue 2
Abstract
Background: Polycystic ovarian syndrome (PCOS) is a complex heterogeneous endocrine disorder. It is a common disorder affecting 4-12% of women of reproductive age. Aims and Objectives: To Study effectiveness of Exercise for the management of infertility in the patients of PCOD. Methodology: After the permission of Institutional ethical committee this prospective study was carried out. 61 women who diagnosed PCOS at the Department of OBGY of a tertiary health care during the one year period i.e. January 2016 to January 2017 were included into study. Those who want to participate the exercise program for six month were included in Study group (n=29) the women who were not willing to participate in the exercise program were enrolled in control group (32). All the women completed the study without any complications. For hirsutism ferriman-gallwey semi quantitative scoring was used and for Acne Global acne grading system 13 was calculated The data was analyses at 6mnoth period after treatment. The statistical analysis paired t-test and chi-square test was applied. Result :Variables of Control and study group were significantly differed i.e. Average Body weight (kg) 83.64 ± 3.12, And 74.96 ± 1.32 (t = 13.89, df = 59, P＜.0001), Average BMI (kg/m2)-33.85 ± 1.11, 27.85 ± 1.24 ( t = 20.10, df = 59, P＜.0001, Average Waist circumference (cm)-101.23 ± 2.92, 95.12 ±1.34 (t=19.34, df = 59 P＜.001), Average Hirsutism score-19.13 ± 4.65, 12.43 ± 2.54 (t=11.2,df = 59 P＜.01). Menstrual history of Control and Study group differed significantly, Average Number of menstrual cycles 4.92 ± 1.21 and 7.92 ±1.1 (t = 10.09, df = 59, P<0.001). Amenorrhea, Oligomenorrhea, Regular cycles was of control and study were 31.03%, 51.72 %, 0.0% and 37.5%, 20.68%, 62.5% respectively.( χ2=21.13,df=2,P<0.001). Fertility parameters studied by Ultrasound like average Antral follicle count in Study group i.e. (AFC) 13.1 ± 3.62 was significantly more in control group i.e. 8.92 ± 4.72. (t=11.22, df = 59, P<0.001), but Total ovarian volume (CC) was not differed in the two groups i.e. 13.12 ±6.52, 12.92 ± 5.82 respectively in control and study group. Effect of Clomiphene in two different groups; Average Ovulation per treatment cycle differed significantly in control group i.e. O.42± 0.13 as compared to study group 1.62 ± 0.23 (t=9.23 df = 59, P<0.01), but the pregnancy outcome like Pregnancy loss among patients who conceived were good in study group i.e. 3/14 (21.42%) as compared to 3/4 (75%) but this is not statistically significant ( χ2=1.969, df=1,P<0.1606). Conclusion: It can be concluded from our study that the 3 month home based aerobic exercise program significantly improved the fertility parameters like average Antral follicle count, Average Ovulation per clomiphene treatment cycle, More no of Regular cycles of menstruation also the parameters like Average Hirsutism score. Average Body weight, Average BMI, Average Waist circumference were significantly reduced. So from our study we recommend 3 month home based aerobic exercise program for the improvement of PCOS symptoms.
Authors and Affiliations
Sharon Deepthi Rasquinha, Richard Santosh Martis, Victor Rasquinha
Keywords
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