Effect of isometric handgrip test on heart rate variability in primary open angle glaucoma
Journal Title: Indian Journal of Clinical Anatomy and Physiology - Year 2017, Vol 4, Issue 1
Abstract
Introduction: Open angle glaucoma is a chronic, slowly progressive optic neuropathy characterised by progressive visual field loss. At systemic level; hypertension, hypotension leading to reduced ocular blood flow (OBF), vasospasm, oxidative stress and cardiovascular disease history are associated with glaucoma. Various studies suggest a relation between Open angle glaucoma (OAG) and autonomic dysfunction, yet the exact mechanism is still unclear. Heart rate variability (HRV) and a provocative cardiac stress test can provide an easy, non-invasive and indirect assessment of the autonomic control of the heart. Material and Method: The present study consists of 20 patients with Primary Open angle Glaucoma (group ІІ) and 20 age & sex matched healthy controls (group І). Frequency domain analysis of HRV at rest and during Handgrip testing was analysed. Results: On immediate release of handgrip patients with POAG depicted a significant raised Low frequency variables LF (nu) (73.39± 4.04), (p < 0.000) and LF/HF ratio (2.79±0.17), (p < 0.000). On the other hand there is a step decrease in high frequency variable HF (nu) (32.04±1.83) in group ІІ (p = 0.002).The decrease in HF (nu) (38.40±8.07), (p < 0.000) with high LF/HF (1.55±0.28), (p<0.000) in group ІІ remained significant during recovery period. Conclusion: The study thus concluded sympathetic overdrive in response to stress and low parasympathetic activity during recovery period suggestive of impaired autonomic activity in Primary Open angle Glaucoma.
Authors and Affiliations
Arijita Banerjee, Indu Khurana
Keywords
Related Articles
- EP ID EP292759
- DOI 10.18231/2394-2126.2017.0002
- Views 61
- Downloads 0
Cardiovascular disease among patients admitted to medicine intensive care unit (MICU) in tertiary care hospital
Introduction Cardiovascular diseases CVDrsquos are rampantly increasing in the Indian population with an increasing trend in the younger patients Overall cardiovascular diseases showed that almost onefourth of all deaths...
Comparative study of resting and post exercise pulse rates between students of medical education and physical education- a cross sectional study
Medical colleges in India have traditionally followed a curriculum stuffed with a large body of knowledge pertaining to asic sciences and clinical disciplines. With expanding body of knowledge, there is over-burdening o...
A comparative study of electrocardiographic QRS complex in asymptomatic obese young adults
Background: Standard 12-lead ECG is widely used initial screening test for non-invasive detection of cardiovascular changes in obesity. It is seen that obesity is associated with leftward shift of the P wave, QRS and T w...
Study of Serum Triglyceride in obese and non-obese subject
The global epidemic of overweight and obesity is rapidly becoming a major public health problem in many parts of the world. Rapidly changing diets and lifestyles are fueling the global obesity epidemic. It is associated...
Estimation of human stature from ulnar length in rural region of Maharashtra
Introduction: Greek anthropos means “man” and metron is “measure” therefore measurement of man- provides scientific methods and techniques for taking various measurements and observation on the living being and the skele...