Effect of Smoking on Cirrhosis with Heavy Alcohol Consumption
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 9
Abstract
Term and quantity of alcohol consumption is one of the most significant factors in terms of occurrence of alcoholic liver disease. In some studies, it has been found out that due to prevalence of smoking-related morbidity, reason of death of alcoholics is more probably smoking related diseases more than alcohol-related disorders.In this study, we aimed to determine characteristics of smoking in cirrhosis with heavy alcohol consumption, its effect on mortality and risk factors.401 cirrhotic patients with heavy alcohol consumption applying to gastroenterology clinic between the years of 2008-2018 successively were assessed retrospectively. Patients used to consume alcohol minimum 40 g/day a day and for more than 10 years. Term of alcohol abuse, type of alcohol and smoking condition were questioned for the patients. Patients with GIS malignity and diseases other than liver were not included in the study. Patients were divided into 3 groups as smoker, ex-smokers and non-smokers. Rate of smoking was found as 90.3%. Age of starting alcohol and body mass index was found as significantly lower in patients who have still smoked. Quantity of daily alcohol use in smokers was significantly higher. In multi-variate analysis, age and quantity of smoking was significantly related to the mortality. Mortality was found less in persons abusing alcohol with strength of 15% above.In our study, smoking has been found as related to the mortality in cirrhosis patients with heavy alcohol consumption. For this reason, we suppose that quitting smoking will be beneficial for increasing rate of survival in in cirrhosis patients with heavy alcohol consumption.
Authors and Affiliations
Sezgin Vatansever, ZehraBetul Pakoz, Sami Deniz, Belkis Unsal
Keywords
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