Effect of Type2 Diabetes Mellitus on Sudanese Male Fertility
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 6
Abstract
Abstract: The main objective of the study was to evaluate the effect of type2 diabetes mellitus on Sudanese male fertility. The second objective was to correlate the presence of hypogonsdism in diabetic subjects with age, glycemic control and duration of diabetes. A cross sectional study conducted on 300 men with type2 diabetes mellitus aged >40 years and 100 healthy men age matched. Total testosterone, follicle stimulating hormone, lutenizing hormone and HbA1c were measured. Data about age and duration of diabetes were collected. Results were computed using SPSS (statistical package for social science) software. Significant proportion of diabetic men showed low levels of serum testosterone (hypogonadal), with (78%) had testosterone level below 300 ng/dl (10.4 nmol/liter) and significant increase levels of FSH and LH in hypogonadal patients (P <0.05). The control group included 10% hypogonadal subjects. Testosterone had inverse linear relationship with age of diabetic subjects and no relationships with duration of diabetes and HbA1c. Serum testosterone levels were significantly low in Sudanese diabetic males, this accompanied with significantly high levels of FSH and LH. Testosterone level inversely correlated with age, but not with HbA1c and duration of diabetes. Keywords:Type-2 Diabetes Mellitus, Testosterone, Follicle Stimulating Hormone, Leutenizing Hormone, HbA1c
Authors and Affiliations
Jihan Mohammed Mohieldin, M. Sc. , Noon Babiker, Omer Mohamed Abdalla
Keywords
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