Effects of Dexmedetomidine on Hemodynamic Responses to Tracheal Intubation: A Comparison with Esmolol
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 7
Abstract
Pressure response to laryngoscopy and endotracheal intubation have been long known to be a deleterious phenomenon. Various methods and various drugs to attenuate these changes have been studied. The most recent being dexmedetomidine. It has been shown to be effective.This study was hence conducted to compare esmolol and this new drug to conclude which is better for the same purpose.The study was a randomised controlled trial done on 50 patients who were randomly allocated to two groups. Group I(n=25) received dexmedetomidine 1mcg/kg body weight iv slowly over 10min while Group II received esmolol 100mg iv bolus slow over 30sec. Intubation responses in form of HR and BP were observed.Though none of the drugs were successful in preventing the hemodynamic responses to tracheal intubation dexmedetomidine was found to be better than esmolol.
Authors and Affiliations
Ranjan Kumar Sinha, Nidhi .
Keywords
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