EFFECTS OF ETHANOLIC EXTRACT OF RAPHANUS SATIVUS SEEDS ON FERTILITY HORMONE AND SPERM PARAMETERS IN MALE WISTAR RATS
Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 5
Abstract
This study was conducted to assess the effect of Raphanus sativus extract on the reproductive performance of male wistar rats. a total of 24 male rats were divided into 4 groups(6 of each) namely group A, B,C and D. All groups were given orally 100, 200, 400 and 0.0, mg/kg body weight extract respectively for 30 days. Symptoms caused by acute toxicity were absorbed through the experimental period. At the end of the experiment body weights and sexual organs weights (testes and epididyims) and semen characteristic were determined. Serum was analyzed for testosterone, Follicle-stimulating hormone (FSH), and Luteinizing hormone (LH) levels. The results showed the body weights was significantly (P≤0.01) decreased, while testicular weight increased. In a dose dependant manner following administration of R. sativus extracts. The extract also improved semen characteristics and elevated significantly the level of fertility hormones. it study conclude that the administration of the Raphanus sativus seeds extract improve normal male rats fertility.
Authors and Affiliations
Manhal M. Dafaalla
Keywords
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