Effects of Hyperventilation on Haemodynamics, Partial Pressure of Carbon Dioxide and Acid Base Status in Laparoscopic Surgeries-Randomized Control Study
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 9
Abstract
The aim of the study was to compare the effects of hyperventilation on haemodynamics and partial pressure of carbon dioxide and acid base status with three different respiratory rates and tidal volume of 10 ml /kg . Methods: 90 patients undergoing laparoscopic surgeries under General Anaesthesia were randomized into three groups, with tidal volume of 10 ml/kg and respiratory rate of 12,14,16 per minute. Hemodynamic variables (heart rate and mean arterial pressure) were recorded and End tidal C02, PaC02, pH and Bicarbonate estimation done before, during and after C02 pneumoperitoneum. Results: The three groups were similar in demographic profile.There were no significant difference in mean arterial pressure before creation of pneumoperitoneum in all three groups. (p value 0.067). Arterial blood gas analysis demonstrated higher PaCO2 and lower pH in control group than in study group. PaCO2 values measured before pneumoperitoneum showed a higher value in group 1 whereas it was lower in normal range in groups 2 and 3 .The values were 34.92 mm of Hg and 33.13 mm of Hg respectively and statistically significant (p value is 0.0000). Heart rate was significantly higher in the control group than the study groups during pneumoperitoneum Peak inspiratory pressure did not suffer significantly between the groups and the p value was 0.976. During the pneumoperitoneum the groups 2 and 3 showed a significantly higher values than the group 1 ( p 0.000.) Conclusions: During laparoscopic surgeries and increasing the minute ventilation by increasing the respiratory rate from 12 per minute to 14 per minute produces a significant decrease in partial pressure of carbon dioxide ,end tidal carbon dioxide and pH .
Authors and Affiliations
Dr Gayathri B
Keywords
Related Articles
- EP ID EP528360
- DOI -
- Views 89
- Downloads 0
Swyer Syndrome: A Rare Cause of Primary Amenorrhoea
Swyer syndrome, which is pure XY gonadal dysgenesis, is an extremely rare condition, presents with primary amenorrhea, female phenotype and male genotype with fibrous streak gonads. We report a case of Swyer syndrome in...
A Rare Case of Isolated Pleural Metastasis of Osteosarcoma
INTRODUCTION Osteosarcoma is the most common primary bone tumor in children and young adults arising from primitive mesenchymal bone-forming cells. Metastasis from osteosarcoma is most commonly to lungs, bone, brain and...
Seroprevalence of Transfusion Transmitted Infection (TTI) among Healthy Blood Donor and Their Distribution within Blood Groups - A Study from Kolkata
Introduction: Blood transfusion is an integral and life saving procedure of modern medicine, but simultaneously it carries the risk of transmitting the life- threatening transfusion-transmissible infectious agents such a...
A Prevalence of Hypertension in Children – School Based Study
Objectives: To study the prevalence and aetiology of Hypertension in school children aged 10-15 Years. Methods: In this study 975 students from 3 Govt. Schools and 975 Students from 4 Pvt. Schools of age group of 10 – 15...
Comparison of Fentanyl and Dexmedetomidine added to low dose Bupivacaine Heavy for Spinal Anaesthesia in Lower Abdominal Surgeries
Spinal anaesthesia is the most commonly used technique for below umbilical surgeries. It is economical, easy to administer and relatively safer. It is important to limit the block level for minimizing hemodynamic changes...